Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using PET/CT to monitor head and neck cancer after treatment

Official title: PET/CT Follow up for Head and Neck Squamous Cell Carcinoma

Run by Copenhagen University Hospital, Rigshospitalet · NCT05707078 · Data updated 2026-11-12

This study is testing if a special imaging scan can help find any return of head and neck cancer in patients who have finished their treatment.

More Head and Neck Squamous Cell Carcinoma trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment600 (estimated)
SponsorCopenhagen University Hospital, Rigshospitalet
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Copenhagen, Copenhagen)
StatusRecruiting
StartedMarch 7, 2023
Main results expectedDecember 30, 2028
Study endsDecember 30, 2030
Registry record updatedAugust 12, 2026
Trial IDNCT05707078 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 who have completed curative treatment for HNSCC of the oral cavity, nasopharynx, oropharynx, hypopharynx, or larynx.

Probably not a fit

Patients who have refused participation, have clinical N0 neck, or are clinically inoperable for any reason may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of 18F-fluorodeoxy-D-glucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) in detecting recurrences of head and neck squamous cell carcinoma (HNSCC) in patients who have completed curative treatment. The research focuses on patients who have undergone radiotherapy for HNSCC, aiming to enhance early detection of potential cancer recurrence. By following established guidelines, the study seeks to improve patient outcomes through timely interventions based on PET/CT findings.

Why it matters

Potential benefit: If successful, this study could lead to earlier detection of cancer recurrence, allowing for more effective salvage treatments.

How similar studies have gone: Other studies have shown promise in using PET/CT for monitoring cancer recurrence, suggesting that this approach may be effective.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Informed consent
* Age above 18
* Completed curative treatment for HNSCC of the oral cavity, nasopharynx, oropharynx, hypopharynx or larynx

Exclusion Criteria:

* Patient refusal
* Patients with clinical N0 neck
* Patients who had neck dissections prior to radiotherapy
* Patients who are clinical inoperable for any reason

Where it's running

  • Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet
    Copenhagen, Copenhagen, Denmark
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.