Using PET/CT to monitor head and neck cancer after treatment
Official title: PET/CT Follow up for Head and Neck Squamous Cell Carcinoma
Run by Copenhagen University Hospital, Rigshospitalet · NCT05707078 · Data updated 2026-11-12
This study is testing if a special imaging scan can help find any return of head and neck cancer in patients who have finished their treatment.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | Copenhagen University Hospital, Rigshospitalet Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Copenhagen, Copenhagen) |
| Status | Recruiting |
| Started | March 7, 2023 |
| Main results expected | December 30, 2028 |
| Study ends | December 30, 2030 |
| Registry record updated | August 12, 2026 |
| Trial ID | NCT05707078 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 who have completed curative treatment for HNSCC of the oral cavity, nasopharynx, oropharynx, hypopharynx, or larynx.
✕Probably not a fit
Patients who have refused participation, have clinical N0 neck, or are clinically inoperable for any reason may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effectiveness of 18F-fluorodeoxy-D-glucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) in detecting recurrences of head and neck squamous cell carcinoma (HNSCC) in patients who have completed curative treatment. The research focuses on patients who have undergone radiotherapy for HNSCC, aiming to enhance early detection of potential cancer recurrence. By following established guidelines, the study seeks to improve patient outcomes through timely interventions based on PET/CT findings.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection of cancer recurrence, allowing for more effective salvage treatments.
How similar studies have gone: Other studies have shown promise in using PET/CT for monitoring cancer recurrence, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Informed consent * Age above 18 * Completed curative treatment for HNSCC of the oral cavity, nasopharynx, oropharynx, hypopharynx or larynx Exclusion Criteria: * Patient refusal * Patients with clinical N0 neck * Patients who had neck dissections prior to radiotherapy * Patients who are clinical inoperable for any reason
Where it's running
-
Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet
Copenhagen, Copenhagen, Denmark Recruiting
Study contacts
- Study coordinator: Jacob H Rasmussen, MD; PhD
- Email: jacob.hoeygaard.rasmussen.01@regionh.dk
- Phone: +4535453251
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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-
Omni 128 cm PET/CT imaging system: comparing new scanner with standard PET/CT
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ABBV-253 in adults with advanced solid tumors
This study tests ABBV-253 to see if it is safe, how it affects the cancer, and how the drug moves in the body for adults with advanced solid tumors.
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Online Sharing for Head & Neck Cancer Support
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Telisotuzumab Adizutecan with Pembrolizumab as first-line treatment for recurrent or metastatic head and neck cancer
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.