Using PET/CT to monitor head and neck cancer after treatment
PET/CT Follow up for Head and Neck Squamous Cell Carcinoma
This study is testing if a special imaging scan can help find any return of head and neck cancer in patients who have finished their treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 600 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Rigshospitalet, Denmark Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Copenhagen) |
| Trial ID | NCT05707078 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of 18F-fluorodeoxy-D-glucose (FDG) Positron Emission Tomography/Computed Tomography (PET/CT) in detecting recurrences of head and neck squamous cell carcinoma (HNSCC) in patients who have completed curative treatment. The research focuses on patients who have undergone radiotherapy for HNSCC, aiming to enhance early detection of potential cancer recurrence. By following established guidelines, the study seeks to improve patient outcomes through timely interventions based on PET/CT findings.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 who have completed curative treatment for HNSCC of the oral cavity, nasopharynx, oropharynx, hypopharynx, or larynx.
Not a fit: Patients who have refused participation, have clinical N0 neck, or are clinically inoperable for any reason may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection of cancer recurrence, allowing for more effective salvage treatments.
How similar studies have performed: Other studies have shown promise in using PET/CT for monitoring cancer recurrence, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Informed consent * Age above 18 * Completed curative treatment for HNSCC of the oral cavity, nasopharynx, oropharynx, hypopharynx or larynx Exclusion Criteria: * Patient refusal * Patients with clinical N0 neck * Patients who had neck dissections prior to radiotherapy * Patients who are clinical inoperable for any reason
Where this trial is running
Copenhagen
- Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet — Copenhagen, Denmark (Recruiting)
Study contacts
- Study coordinator: Jacob H Rasmussen, MD; PhD
- Email: jacob.hoeygaard.rasmussen.01@regionh.dk
- Phone: +4535453251
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.