Using PET/CT imaging to diagnose TSPO-related diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the effectiveness of 18F-DPA714/FDPA positron emission tomography/computed tomography (PET/CT) in diagnosing primary and metastatic lesions in patients with various TSPO-related diseases, including neuroinflammation and neurodegenerative conditions. Participants, who are adults with suspected or diagnosed malignant tumors, undergo PET/CT scans to assess lesion uptake and quantify results using maximum standard uptake value (SUVmax). The study aims to calculate key diagnostic metrics such as sensitivity, specificity, and accuracy of the imaging technique.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- (i) adult patients (aged 18 years or order); (ii) patients with suspected or new diagnosed or previously treated malignant tumors (supporting evidence may include MRI, CT, tumor markers and pathology report); (iii) patients who had scheduled TSPO PET/CT scan; (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

Exclusion Criteria:

\- (i) patients with non-malignant lesions; (ii) patients with pregnancy; (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

Where it's running

• The First Affiliated Hospital of University of Science and Technology of China
  Hefei, Anhui, China Recruiting
• The Affiliated Hospital of Qingdao University
  Qingdao, Shandong, China Recruiting
• Tianjin Medical University General Hospital
  Tianjin, Tianjin Municipality, China Recruiting

Study contacts

• Study coordinator: Ying Wang
• Email: macrossplusvoices@163.com
• Phone: +8618702292537

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.