Using ozonized olive oil to treat periodontal pockets

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of ozonized olive oil gel in treating periodontal pockets in patients diagnosed with chronic periodontitis. Sixteen participants were randomly assigned to either an experimental group receiving the ozonized olive oil gel or a control group receiving a placebo gel. After an initial hygiene treatment to remove tartar, the participants underwent a series of evaluations and gel administrations over a three-week period, including periodontal probing and microbiological sampling to assess treatment outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with stage II, III, or IV periodontitis according to the new 2017 World Workshop periodontal classification
* Patients of either sex and older than 18 years of age
* Probing Pocket Depth (PPD) greater than or equal to 4 mm at 3 sites
* Patients who have signed consent to the study
* Collaborating patients

Exclusion Criteria:

* age \< 18 years and/or inability to provide written informed consent;
* absence of family or social welfare support;
* non-drug-induced gingival hypertrophy,
* severe smokers (more than 20 cigarettes per day),
* consumers of high levels of alcohol,
* patients on corticosteroid treatment,
* diabetic patient,
* immunodepressive therapies,
* chemotherapies,
* radiotherapies,
* pregnancy states;
* lack of collaboration for ongoing postoperative reevaluations.

Where it's running

• Odontostomatologic Departement of Policlinic of Bari
  Bari, Ba, Italy Recruiting

Study contacts

• Principal investigator: Massimo Petruzzi, PhD, MD — University of Bari
• Study coordinator: Fabio Vittorio Ciccone, MD
• Email: fabio.ciccone5@gmail.com
• Phone: 3887589165

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.