Using organosilane for cleaning surfaces in intensive care units
Organosilane for Surface Cleaning in Intensive Care Units: A Cluster Randomized, Controlled, Crossover, Clinical Trial
This study tests if using a new cleaning method with organosilane can help reduce infections in patients in intensive care units compared to just regular cleaning.
Quick facts
| Phase | Phase2; Phase3 |
|---|---|
| Study type | Interventional |
| Enrollment | 13000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospital Israelita Albert Einstein Academic / other |
| Locations | 14 sites (Belo Horizonte and 13 other locations) |
| Trial ID | NCT05673226 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of surface disinfection using organosilane in conjunction with traditional cleaning methods to reduce healthcare-associated infections (HAIs) in intensive care units. It compares the incidence of infections in patients admitted to ICUs that implement this new cleaning protocol against those that rely solely on traditional cleaning. The study aims to determine if the addition of organosilane can significantly lower the rates of infections such as pneumonia and catheter-related infections.
Who should consider this trial
Good fit: Ideal candidates for this study are patients aged 18 years and older who are being admitted to participating intensive care units.
Not a fit: Patients under 18 years and those in ICUs already using organosilane for surface disinfection will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to a significant reduction in healthcare-associated infections in intensive care settings, improving patient outcomes.
How similar studies have performed: Other studies have shown promising results with enhanced cleaning protocols in reducing infection rates, suggesting that this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients aged 18 years and older who will be admitted to the participating ICUs Exclusion Criteria: * Patients under 18 years * ICUs that may use any organosilane formulation for surface disinfection
Where this trial is running
Belo Horizonte and 13 other locations
- Santa Casa de Misericórdia — Belo Horizonte, Brazil (Recruiting)
- Hospital Jean Bittar — Belém, Brazil (Recruiting)
- Hospital de Base do Distrito Federal — Brasília, Brazil (Recruiting)
- Hospital Universitário de Brasília — Brasília, Brazil (Recruiting)
- Hospital Otoclínica — Fortaleza, Brazil (Recruiting)
- Hospital Geral de Goiânia — Goiânia, Brazil (Recruiting)
- Hospital do Tricentenário — Olinda, Brazil (Recruiting)
- Hospital Escola Universidade Federal de Pelotas — Pelotas, Brazil (Recruiting)
- Hospital Ernesto Dornelles — Porto Alegre, Brazil (Recruiting)
- Hospital Ana Nery — Salvador, Brazil (Recruiting)
- Hospital Santa Cruz — Santa Cruz Do Sul, Brazil (Recruiting)
- Hospital Presidente Vargas — São Luís, Brazil (Recruiting)
- A.C. Camargo Cancer Center — São Paulo, Brazil (Recruiting)
- Hospital do Coração — São Paulo, Brazil (Recruiting)
Study contacts
- Study coordinator: Antonio P Nassar Jr, PhD
- Email: antonio.nassar@einstein.br
- Phone: 551121519617
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.