Using NSAIDs for pain management during pleurodesis procedures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the safety and efficacy of non-steroidal anti-inflammatory drugs (NSAIDs) in managing pain during pleurodesis procedures for patients with pneumothorax. The study aims to determine whether NSAIDs can effectively reduce pain without increasing the risk of pneumothorax recurrence. Participants will receive either ketoprofen or a placebo during their pleurodesis surgery. The trial is designed to assess the balance between effective pain management and potential complications associated with NSAID use.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age≥18-year-old
* pneumothorax with an indication of pleurodesis
* with or without minimal lung resection
* via thoracotomy or thoracoscopy

Exclusion Criteria:

* Minor patient
* Pregnant, parturient or breast-feeding patient
* Severe polytrauma (associated with the presence of a Vittel criterion)
* Purulent pleurisy
* Hemopneumothorax
* Lactose hyper sensibility
* Contraindications to NSAID
* Contraindications to tramadol
* Contraindications to paracetamol
* Curative anticoagulation
* Patients under guardians or deprived of their liberty
* Patient refusal

Where it's running

• Centre Hospitalier Universitaire d'Amiens
  Amiens, France Recruiting

Study contacts

• Study coordinator: Florent LEVIEL, MD
• Email: leviel.florent@chu-amiens.fr
• Phone: 33 3 22 08 91 09

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.