Using NMS Assist to help people with Parkinson's manage non-motor symptoms

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Parkinson's can cause a range of non-motor symptoms such as pain, sleep, mood and memory problems that often go unrecognized and reduce quality of life. In this single-site interventional project, 30 people with clinically diagnosed Parkinson's and their care partners will use the NMS Assist mobile system for six months while researchers record app usage and collect user-reported changes in knowledge, confidence, and symptom tracking. A smaller subgroup will take part in detailed interviews to explore user experience and help refine the tool's usability. Outcomes focus on engagement and user experience, with secondary measures including self-reported self-management ability and communication with healthcare professionals.

Why it matters

Who can join: the full rules

Inclusion Criteria: Individuals will be eligible if they meet the following inclusion criteria:

All:

* Age 18 years or over
* Have compatible smartphone/data access (access to a digital device is a necessary prerequisite of system use, and the formative usability study had success in recruiting participants with varying levels of experience with smartphones)
* Be fluent in English
* Able and willing to provide informed consent
* Able and willing to comply with intervention requirements

For clinically diagnosed people with Parkinson's (PwP) (ICD-10-CM G20):

* Not resident in a care home or nursing home
* Ambulant
* Interested in monitoring and managing their NMS

For CPs:

\- Be caring for a clinically diagnosed PwP (ICD-10-CM G20) who is participating in the study

Exclusion Criteria: Participants will be ineligible for the study if they meet any of the following exclusion criteria:

All:

* Previous involvement in the development or testing of the digital system
* In a dependent/unequal relationship with the research or care teams or any PPI representatives

PwP:

* Secondary cause of Parkinsonism
* Significant cognitive impairment or a diagnosis of Parkinson's disease dementia
* Significant comorbidity, which, in the opinion of the chief investigator, would preclude safe participation in the study or protocol compliance
* A life expectancy of \<6 months
* Living in residential care facilities

Where it's running

• Newcastle University
  Newcastle upon Tyne, Tyne and Wear, United Kingdom Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.