Using neuromodulation to treat pain from chemotherapy-induced peripheral neuropathy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of neuromodulation in alleviating pain associated with chemotherapy-induced peripheral neuropathy (CIPN). It will involve patients diagnosed with lower extremity CIPN due to specific chemotherapy agents, who will undergo sensory testing and evaluation of peripheral neuropathy markers. The study will take place at the Pain Management Center at MD Anderson Cancer Center, focusing on a single-center feasibility approach. Participants will be monitored for changes in pain levels and nerve function as a result of the intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Ability to understand and the willingness to sign a written informed consent document
* Patients diagnosed with CIPN lower extremity due to either vinca alkaloids, taxanes, bortezomib, thalidomide, platinum-based compounds
* Patients seen at Pain Management Center at MD Anderson Cancer Center
* Patient ages greater or equal to 18 years but less than or equal to 85 years

Exclusion Criteria

* Patients with cognitive dysfunction
* Patient with recent history (\<6 months) of drug or alcohol abuse
* Patients with open skin lesion or undergoing antibiotic therapy for local for systemic infection
* Patients with painful diabetic peripheral neuropathy or preexisting peripheral neuropathy

Where it's running

• M D Anderson Cancer Center
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Saba Javed, M D — M.D. Anderson Cancer Center
• Study coordinator: Saba Javed, M D
• Email: sjaved@mdanderson.org
• Phone: (713) 792-9530

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.