Using Negative Pressure Therapy to Prevent Infections in Surgical Wounds
Official title: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial
Run by Gulab Devi Hospital · NCT06957964 · Data updated 2026-11-12
This study is testing if using Negative Pressure Therapy can help prevent infections in surgical wounds for people who have had laparotomy surgery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 70 Years |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | Gulab Devi Hospital Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | March 25, 2025 |
| Main results expected | June 25, 2025 |
| Study ends | June 25, 2025 |
| Registry record updated | May 6, 2025 |
| Trial ID | NCT06957964 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 20 to 70 who are undergoing laparotomy under general anesthesia and are classified as ASA I-II.
✕Probably not a fit
Patients who are pregnant, have undergone previous surgeries that complicate their condition, or cannot adhere to follow-up instructions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial involves 70 participants who will undergo laparotomy and be randomly assigned to either receive Negative Pressure Wound Therapy or standard care without it. The aim is to assess the effectiveness of Negative Pressure Therapy in preventing surgical site infections post-surgery. Participants will be monitored for 30 days after discharge, and any infections will be treated according to hospital protocols. Data will be collected to evaluate the outcomes of both treatment groups.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of infections in surgical wounds, improving patient recovery and outcomes.
How similar studies have gone: Previous studies have shown promising results with Negative Pressure Wound Therapy in similar contexts, suggesting potential effectiveness in this trial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients of age between 20 to 70 years, both genders * Undergoing laparotomy under general anaesthesia * ASA I-II Exclusion Criteria: * Patients who did not complete the follow up instructions * Pregnant patients * Patients already undergone a relook laparotomy, if their abdomen is left open or if unable to adhere
Where it's running
-
Gulab Devi Hospital Lahore
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Study coordinator: Dr Hamail Khanum, MBBS
- Email: hamailkhanum@gmail.com
- Phone: +923235511997
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.