Using Negative Pressure Therapy to Prevent Infections in Surgical Wounds
Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial
This study is testing if using Negative Pressure Therapy can help prevent infections in surgical wounds for people who have had laparotomy surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 20 Years to 70 Years |
| Sex | All |
| Sponsor | Gulab Devi Hospital Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Trial ID | NCT06957964 on ClinicalTrials.gov |
What this trial studies
This clinical trial involves 70 participants who will undergo laparotomy and be randomly assigned to either receive Negative Pressure Wound Therapy or standard care without it. The aim is to assess the effectiveness of Negative Pressure Therapy in preventing surgical site infections post-surgery. Participants will be monitored for 30 days after discharge, and any infections will be treated according to hospital protocols. Data will be collected to evaluate the outcomes of both treatment groups.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 to 70 who are undergoing laparotomy under general anesthesia and are classified as ASA I-II.
Not a fit: Patients who are pregnant, have undergone previous surgeries that complicate their condition, or cannot adhere to follow-up instructions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of infections in surgical wounds, improving patient recovery and outcomes.
How similar studies have performed: Previous studies have shown promising results with Negative Pressure Wound Therapy in similar contexts, suggesting potential effectiveness in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients of age between 20 to 70 years, both genders * Undergoing laparotomy under general anaesthesia * ASA I-II Exclusion Criteria: * Patients who did not complete the follow up instructions * Pregnant patients * Patients already undergone a relook laparotomy, if their abdomen is left open or if unable to adhere
Where this trial is running
Lahore, Punjab Province
- Gulab Devi Hospital Lahore — Lahore, Punjab Province, Pakistan (Recruiting)
Study contacts
- Study coordinator: Dr Hamail Khanum, MBBS
- Email: hamailkhanum@gmail.com
- Phone: +923235511997
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.