Clinical trial Recruiting at 1 site Interventional Ages 20 to 70

Using Negative Pressure Therapy to Prevent Infections in Surgical Wounds

Official title: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial

Run by Gulab Devi Hospital · NCT06957964 · Data updated 2026-11-12

This study is testing if using Negative Pressure Therapy can help prevent infections in surgical wounds for people who have had laparotomy surgery.

Quick facts

Study typeInterventional
Ages20 Years to 70 Years
SexAll
Enrollment70 (estimated)
SponsorGulab Devi Hospital
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedMarch 25, 2025
Main results expectedJune 25, 2025
Study endsJune 25, 2025
Registry record updatedMay 6, 2025
Trial IDNCT06957964 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 20 to 70 who are undergoing laparotomy under general anesthesia and are classified as ASA I-II.

Probably not a fit

Patients who are pregnant, have undergone previous surgeries that complicate their condition, or cannot adhere to follow-up instructions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial involves 70 participants who will undergo laparotomy and be randomly assigned to either receive Negative Pressure Wound Therapy or standard care without it. The aim is to assess the effectiveness of Negative Pressure Therapy in preventing surgical site infections post-surgery. Participants will be monitored for 30 days after discharge, and any infections will be treated according to hospital protocols. Data will be collected to evaluate the outcomes of both treatment groups.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the incidence of infections in surgical wounds, improving patient recovery and outcomes.

How similar studies have gone: Previous studies have shown promising results with Negative Pressure Wound Therapy in similar contexts, suggesting potential effectiveness in this trial.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients of age between 20 to 70 years, both genders
* Undergoing laparotomy under general anaesthesia
* ASA I-II

Exclusion Criteria:

* Patients who did not complete the follow up instructions
* Pregnant patients
* Patients already undergone a relook laparotomy, if their abdomen is left open or if unable to adhere

Where it's running

  • Gulab Devi Hospital Lahore
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.