Using navigators to deliver electronic patient-reported outcomes for cancer patients

Evaluating the Implementation and Impact of Navigator-delivered ePRO Home Symptom Monitoring and Management

NA · University of Alabama at Birmingham · NCT04809740

This study is testing whether using navigators to help cancer patients report their symptoms electronically during chemotherapy can improve their care and outcomes.

Quick facts

PhaseNA
Study typeInterventional
Enrollment7500 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Alabama at Birmingham (other)
Drugs / interventionschemotherapy, immunotherapy
Locations2 sites (Birmingham, Alabama and 1 other locations)
Trial IDNCT04809740 on ClinicalTrials.gov

What this trial studies

This study evaluates the implementation of a navigator-delivered electronic patient-reported outcomes (ePRO) system for cancer patients receiving chemotherapy across multiple practice sites. It aims to identify barriers and facilitators to the implementation of this system and assess its impact on clinical outcomes and healthcare utilization. The study will leverage existing infrastructure from Medicare's payment reform projects to support the delivery of ePROs, focusing on improving outcomes for vulnerable populations. The research will utilize a hybrid design to test the effectiveness of these implementation strategies.

Who should consider this trial

Good fit: Ideal candidates for this study are adult cancer patients aged 18 and older who are receiving chemotherapy, targeted therapy, or immunotherapy at the participating institutions.

Not a fit: Patients who are only seeking a second opinion at the participating institution will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the quality of life and overall survival of cancer patients by improving symptom monitoring and healthcare utilization.

How similar studies have performed: Previous studies have shown success with similar electronic home-based patient-reported outcomes interventions, indicating potential for effective implementation in real-world settings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patient Group:

* Age ≥18
* Cancer patients at participating institution
* Receipt of chemotherapy, targeted therapy, and immunotherapy at participating institution from 2019-2026.

Exclusion Criteria:

- Second opinion only at participating institution.

Where this trial is running

Birmingham, Alabama and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.