Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using muscle assessment to predict health outcomes in liver disease patients

Official title: MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease

Run by University of Chicago · NCT05264051 · Data updated 2026-11-12

This study is testing if a quick muscle check during an MRI can help predict health outcomes for patients with liver disease.

More Liver Diseases trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1200 (estimated)
SponsorUniversity of Chicago
Academic / other
Locations1 site (Chicago, Illinois)
StatusRecruiting
StartedApril 18, 2022
Main results expectedMarch 1, 2027
Study endsMarch 1, 2027
Registry record updatedJanuary 14, 2026
Trial IDNCT05264051 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients with liver disease who are already scheduled for an MRI for routine clinical purposes.

Probably not a fit

Patients under 18 years of age will not benefit from this study as they are excluded from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the Muscle Assessment Score (MAsS) using MRI as an objective measure of frailty and muscle composition in patients with liver disease. It will involve a prospective analysis of patients already scheduled for MRI at the University of Chicago Medical Center, focusing on four specific groups: those hospitalized with acute hepatic decompensation, patients with hepatobiliary neoplasia, individuals undergoing TIPS placement, and those with chronic liver disease. The MAsS assessment will add an additional 8-10 minutes to the MRI procedure, allowing researchers to gather valuable data on the correlation between muscle composition and patient outcomes.

Why it matters

Potential benefit: If successful, this study could provide a new predictive tool for assessing morbidity and mortality risks in liver disease patients.

How similar studies have gone: While the use of muscle assessment in liver disease is a growing area of interest, this specific approach utilizing MAsS and MRI is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who are already scheduled for an MRI for routine clinical purposes will be evaluated

Exclusion Criteria:

* \<18 yrs. of age

Where it's running

  • The University of Chicago
    Chicago, Illinois, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.