Using MRI to predict metastasis in soft tissue sarcoma patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of diffusion-weighted magnetic resonance imaging (DWI) combined with intravoxel incoherent motion (IVIM) to assess tumor hypoxia in patients with soft tissue sarcoma (STS). By identifying hypoxia, which is linked to metastasis, the study aims to enable personalized treatment strategies at the time of diagnosis without adding significant burden to patients or clinical workflows. The approach leverages standard MRI techniques that can be performed quickly, potentially improving patient outcomes through better stratification for treatment. The study is conducted at the University Health Network in Toronto.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Ability to understand and the willingness to sign a written informed consent document
* Grade 2 or 3 soft tissue sarcoma greater than 5 cm in largest dimension

Exclusion Criteria:

* Contraindication to MRI scan as per current institutional guidelines (for patients requiring MRI)

Where it's running

• University Health Network
  Toronto, Ontario, Canada Recruiting

Study contacts

• Study coordinator: David Shultz, MD
• Email: david.shultz@rmp.uhn.ca
• Phone: 416-946-4501

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.