Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using MRI to Measure Soft Tissue Stiffness

Official title: Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues

Run by Ohio State University · NCT01757730 · Data updated 2026-11-12

This study is testing a new way to use MRI scans to see how stiff soft tissues like the liver and heart are, which could help diagnose conditions like liver fibrosis and heart failure more easily.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment1000 (estimated)
SponsorOhio State University
Academic / other
Locations1 site (Columbus, Ohio)
StatusRecruiting
StartedMarch 2012
Main results expectedMarch 1, 2030
Study endsMarch 1, 2030
Registry record updatedOctober 21, 2026
Trial IDNCT01757730 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who are safe for MRI procedures.

Probably not a fit

Patients with unapproved metal implants, those who are pregnant, or individuals with claustrophobia may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study utilizes Magnetic Resonance Elastography (MRE), a non-invasive imaging technique, to assess the stiffness of soft tissues such as the liver, heart, and kidneys. Participants will undergo an MRI scan while a paddle is placed on the area of interest to transmit sound vibrations, which are then captured by the MRI to create stiffness maps. The goal is to provide a more accessible and less invasive method for diagnosing conditions like liver fibrosis and heart failure compared to traditional techniques. MRE has the potential to improve the understanding and management of various diseases affecting soft tissue stiffness.

Why it matters

Potential benefit: If successful, this technique could lead to earlier and more accurate diagnoses of conditions like liver fibrosis and heart failure, improving patient outcomes.

How similar studies have gone: Other studies have shown that Magnetic Resonance Elastography is effective in assessing liver stiffness, indicating a promising approach for similar applications.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Any participant 18 years or older and are MR safe.

Exclusion Criteria:

That study participants will be excluded if they have any unapproved metal in their bodies, or if the volunteers are pregnant or possible of becoming pregnant. Also if the participants are claustrophobic.

Where it's running

  • The Ohio State University Wexner Medical Center
    Columbus, Ohio, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.