Using MRI to evaluate brain health in patients with small vessel disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on cerebral small vessel disease (cSVD), which is a significant cause of ischemic strokes and vascular cognitive impairment. It aims to utilize advanced magnetic resonance imaging (MRI) technologies to detect early changes in brain structures and vascular functions associated with cSVD. By identifying these changes early, the study seeks to improve clinical outcomes through timely interventions. Participants will undergo MRI assessments to evaluate their brain health and cognitive function.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Clinical evidence of cerebral small vessel disease or MRI evidence of lacunar infarcts and white matter hyperintensity
* No disability (modified Rankin's scale \< 2)
* No dementia (MMSE \> 24 and absence of dependence in daily activities)
* Able and willing to consent

Exclusion Criteria:

* Contraindications to MRI
* Standard MRI of bad quality due to movement artefacts
* Pregnant
* Unable to tolerate MRI

Where it's running

• Chinese PLA General Hospital
  Beijing, China Recruiting

Study contacts

• Principal investigator: Xin Lou, MD, PhD — Chinese PLA General Hospital
• Study coordinator: Kun Cheng, M.S.
• Email: dr_chengkun@163.com
• Phone: +8619921784434

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.