Using MRI to assess heart function in patients with acute heart attacks
Official title: Clinical Relevance of Magnetic Resonance Imaging in Acute ST-Elevation Myocardial Infarction
Run by Medical University Innsbruck · NCT04113356 · Data updated 2026-11-12
This study is testing how MRI can help doctors understand heart function in people who have just had their first heart attack.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1500 (estimated) |
| Sponsor | Medical University Innsbruck Academic / other |
| Locations | 2 sites (Innsbruck and 1 other locations) |
| Status | Recruiting |
| Started | January 2011 |
| Main results expected | June 2026 |
| Study ends | June 2031 |
| Registry record updated | September 10, 2021 |
| Trial ID | NCT04113356 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults experiencing their first acute ST-elevation myocardial infarction who can undergo primary percutaneous coronary intervention within 24 hours of symptom onset.
✕Probably not a fit
Patients with a history of previous myocardial infarction, renal failure, or contraindications to MRI will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study evaluates the role of cardiovascular magnetic resonance imaging in patients experiencing their first acute ST-elevation myocardial infarction. The aim is to assess various MRI parameters to understand their clinical significance and impact on patient outcomes. Participants will undergo MRI within 24 hours of receiving primary percutaneous coronary intervention after symptom onset. The study focuses on gathering comprehensive data to improve the understanding of heart function and pathology in this critical condition.
Why it matters
Potential benefit: If successful, this study could enhance the diagnosis and treatment strategies for patients suffering from acute ST-elevation myocardial infarction.
How similar studies have gone: While the use of MRI in cardiac assessments is established, this specific application in acute ST-elevation myocardial infarction is relatively novel and may provide new insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: * First ST-elevation myocardial infarction according to the European Society of Cardiology/American College of Cardiology committee criteria * Primary percutaneous coronary intervention within 24 hours after symptom onset Exclusion criteria: * Age \< 18 years * Any history of a previous myocardial infarction or coronary intervention * Clinically unstable patients (Killip class \>2) * Renal failure (estimated glomerular filtration rate \< 30 ml/min/1.73 m2) * Contraindications to cardiac magnetic resonance imaging (pacemaker, cerebral aneurysm clip, orbital foreign body, known or suggested contrast allergy to gadolinium, claustrophobia) * Inability to provide informed consent
Where it's running
-
University Hospital for Internal Medicine III (Cardiology and Angiology)
Innsbruck, Austria Recruiting -
University Hospital for Radiology
Innsbruck, Austria Recruiting
Study contacts
- Principal investigator: Bernhard Metzler, MD, MSc — University Hospital for Internal Medicine III (Cardiology and Angiology)
- Study coordinator: Bernhard Metzler, MD, MSc
- Email: bernhard.metzler@tirol-kliniken.at
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.