Using morphine during gallbladder surgery to reduce pain
Intraoperative Administration of Intravenous Morphine in Patients Undergoing Laparoscopic Cholecystectomy - a Retrospective, Observational, Quality-improvement Study
Esbjerg Hospital - University Hospital of Southern Denmark · NCT06182111
This study tests if giving morphine during gallbladder surgery can help reduce pain after the operation.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 21 Years and up |
| Sex | All |
| Sponsor | Esbjerg Hospital - University Hospital of Southern Denmark (other) |
| Locations | 1 site (Esbjerg) |
| Trial ID | NCT06182111 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the effects of administering intravenous morphine during laparoscopic cholecystectomy on postoperative pain levels and side effects. Participants will be divided into two groups: one receiving morphine during surgery and the other not receiving morphine. The study will utilize the Redcap secure web application for data collection and management, and statistical analyses will include T-tests and potentially logistic regression. The goal is to determine if morphine can effectively reduce pain after gallbladder removal surgery.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for elective laparoscopic cholecystectomy who can provide consent.
Not a fit: Patients with chronic pain syndromes or those with a history of substance abuse may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved pain management for patients undergoing gallbladder surgery.
How similar studies have performed: Previous studies have shown varying results regarding the effectiveness of intraoperative morphine for pain management, making this approach both relevant and potentially novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients who have had elective laparoscopic cholecystectomy/planned gall-bladder removal surgery Exclusion Criteria: * age limit as above * patients unable to give consent to anesthesia * patients unable to participate in pain scoring * patients with chronic pain syndromes, characterized by patients receiving regular analgesic treatment and patients with active or previous contact to pain clinic) * patients with active or previous substance abuse * emergency surgery
Where this trial is running
Esbjerg
- Hospital of south West Jutland — Esbjerg, Denmark (RECRUITING)
Study contacts
- Principal investigator: Sanne V Nielsen, MD — Esbjerg Hospital - University Hospital of Southern Denmark
- Study coordinator: Sanne V Nielsen, MD
- Email: sanne.vibe.nielsen@rsyd.dk
- Phone: +45 28 49 18 25 (private)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Postoperative Pain, Morphine, Laparoscopic Cholecystectomy, Intraoperative morphine for laparoscopic cholecystectomy