Using mild electrical brain stimulation plus DBT skills training for adults with ADHD

Effects and Mechanisms of Transcranial Direct Current Stimulation Combined With Dialectical Behavior Therapy Skills Training in Adults With Attention-Deficit/Hyperactivity Disorder

Not applicable Interventional Nanjing Medical University · NCT07565402

This trial will try adding mild electrical brain stimulation (tDCS) to DBT skills training to see if it helps adults with ADHD improve attention, impulse control, and daily functioning.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 55 Years
SexAll
SponsorNanjing Medical University Academic / other
Locations1 site (Nanjing, Jiangsu)
Trial IDNCT07565402 on ClinicalTrials.gov

What this trial studies

The study delivers transcranial direct current stimulation (tDCS) alongside Dialectical Behavior Therapy Skills Training (DBT-ST) to right-handed adults aged 18–55 who meet DSM-5 criteria for ADHD as confirmed by the Chinese DIVA-5 diagnostic interview. Participants with neurological or other psychiatric disorders, cranial implants, recent ECT, pregnancy/breastfeeding, severe physical illness, or planned medication changes are excluded. Clinical symptom measures and executive-function tests, and possibly neurophysiological markers, are used to track outcomes and examine mechanisms. Treatment sessions and follow-ups are conducted on site at Nanjing Brain Hospital.

Who should consider this trial

Good fit: Adults 18–55 years old with a DSM-5 diagnosis of ADHD confirmed by DIVA-5, who are right-handed, medically stable, willing to attend in-person sessions, and able to give informed consent are the ideal candidates.

Not a fit: Individuals with other neurological or psychiatric disorders, intracranial metal or electronic implants, recent ECT, pregnancy or breastfeeding, planned ADHD medication changes, or who are not right-handed may not benefit or be eligible.

Why it matters

Potential benefit: If successful, the combined approach could improve attention, impulse control, and everyday functioning more than DBT skills training alone.

How similar studies have performed: Separate small studies have reported modest benefits from tDCS on cognition and from DBT-ST on emotion and behavior, but combining these interventions for adult ADHD is relatively novel and has limited prior evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Meet the diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) according to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Diagnosis confirmed using the Chinese version of the Diagnostic Interview for ADHD in Adults (DIVA-5).
* Aged between 18 and 55 years.
* Right-handed.
* Voluntary participation with provision of written informed consent.

Exclusion Criteria:

* Presence of neurological disorders or other psychiatric disorders.
* Severe physical illness.
* Receipt of electroconvulsive therapy (ECT) or other physical treatments within 6 months prior to enrollment.
* Planned changes in ADHD-related medication before the final follow-up assessment.
* Contraindications to tDCS (e.g., intracranial metal or electronic implants, skull plates, or other cranial implants).
* Pregnancy or breastfeeding.

Where this trial is running

Nanjing, Jiangsu

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Adult Attention Deficit Hyperactivity Disorderadult ADHDtranscranial direct current stimulationdialectical behavior therapyDBT skills trainingexecutive functionresting-state fMRI
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.