Using mental imagery and scents to improve sleep in insomnia patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of mental Imagery Rescripting (IR) and olfactory Targeted Memory Reactivation (TMR) in reducing insomnia severity and hyperarousal in patients with Insomnia Disorder. Participants will be randomized into four groups, receiving different interventions including sleep hygiene education, IR sessions, and TMR during sleep. The aim is to transform negative memories into positive ones and strengthen memory recall to improve sleep quality. The study will assess the impact of these techniques over four weeks.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 45 years
* Insomnia disorder according to the International Classification of Diseases 3 (ICSD-3)
* ISI \> 10
* PSQI \> 5
* No other current treatment for Insomnia

Exclusion Criteria:

* patients with another psychiatric disorder requiring acute treatment according to DSM-5
* patients with medical (e.g. neurological disorders) or other disorders explaining the predominant complaint of insomnia (e.g., sleep apneas with ODI\>15/h, restless legs syndrome, periodic limb movements with PLM\>15, chronic pain)
* patients with significant substance use/withdrawal
* patients with heavy smoking
* known pregnancy
* patients suffering from anosmia, olfactory related issues and respiratory pathology

Where it's running

• Center for Sleep Medicine
  Geneva, Switzerland Recruiting

Study contacts

• Study coordinator: Lampros Perogamvros
• Email: Lampros.Perogamvros@hcuge.ch
• Phone: +41223729946

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.