Using magnesium sulphate to improve muscle relaxation in children during abdominal surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of magnesium sulphate pretreatment on the onset and duration of deep neuromuscular blockade in children undergoing elective open abdominal surgeries. The researchers will compare the efficacy of magnesium sulphate with two neuromuscular blocking agents, rocuronium and Cis-Atracurium. The goal is to enhance surgical conditions and reduce postoperative complications by improving muscle relaxation. The study will involve children aged 2 to 12 years and will monitor the effects of magnesium on neuromuscular function during surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age group 2-12 years old
2. Both genders
3. Children who will be scheduled to undergo elective laparoscopic surgeries.
4. Patients with American Society of Anesthesiologist physical status classification of 1 or 2-

Exclusion Criteria:

1. Patients who are beyond the selected age group.
2. Patients on medications that interfered with muscle activity.
3. Allergy to medications used in this study.
4. Neuro-muscular diseases.
5. Renal or hepatic impairment.
6. Hypermagnesemia (\>2.5 mmol) or hypomagnesemia (\<1.7 mmol).
7. Parental refusal to participate in the study

Where it's running

• Pediatric hospital, faculty of medicine, Assiut university
  Asyut, Assiut Governorate, Egypt Recruiting
• Pediatric hospital
  Asyut, Assiut Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Hala Abdel-Ghaffar, MD — Professor of anesthesia and intensive care, faculty of medicine, Assiut university, Assiut, Egypt.
• Study coordinator: Hala S Abdel-Ghaffar, MD
• Email: hallasaad@yahoo.com
• Phone: 01003812011

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.