Using magnesium sulfate with local anesthetics for pain control after breast surgery
Effect of Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical Mastectomy
NA · Cairo University · NCT06815887
This study tests if adding magnesium sulfate to local anesthesia can help reduce pain after breast surgery for patients undergoing modified radical mastectomy.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 70 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06815887 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of adding magnesium sulfate to local anesthetics in combined Pectoralis Nerve Block II and stellate ganglion block for managing postoperative pain in patients undergoing modified radical mastectomy. The research aims to enhance pain relief by utilizing regional anesthesia techniques that target specific thoracic nerves and sympathetic ganglia. By incorporating magnesium sulfate, known for its analgesic and anti-inflammatory properties, the study seeks to improve the overall pain management strategy for these patients.
Who should consider this trial
Good fit: Ideal candidates include adult females scheduled for elective modified radical mastectomy with a BMI between 20 and 40.
Not a fit: Patients with bleeding disorders, chronic pain syndromes, or those with a history of substance abuse may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and reliance on narcotics for patients after breast surgery.
How similar studies have performed: Previous studies have shown promising results with similar nerve block techniques, but the addition of magnesium sulfate in this specific context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years. * Female gender. * American Society of Anesthesiologists (ASA) physical status II or III. * Patients scheduled for elective modified radical mastectomy for breast cancer. * Body mass index (BMI): \> 20 kg/m2 and \< 40 kg/m2. Exclusion Criteria: * Bleeding tendency due to coagulopathy, * Patients with opioid dependence or alcohol or drug abuse, * Significant liver and renal sufficiency * Patients with psychiatric illnesses that prevent them from proper perception and assessment of pain. * Local infection at the site of the block. * Known hypersensitivity or allergy to magnesium sulfate or local anesthetics. * Patients with chronic pain syndromes or pre-existing neuropathic pain conditions. * Pregnant or lactating individuals.
Where this trial is running
Cairo
- Cairo University — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Mahmoud A Ali, Master
- Email: dr.ambitious2@gmail.com
- Phone: 00201096799233
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Magnesium Sulfate, Local Anesthetic, Pectoral Nerve, Stellate Ganglion Block, Postoperative Pain, Modified Radical Mastectomy