Using machine learning to improve digital mental health interventions
Official title: Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions
Run by Boston University Charles River Campus · NCT05567640 · Data updated 2026-11-12
This study is testing if using machine learning can help find the best digital mental health program for people with anxiety and depression to improve their care and results.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1800 (estimated) |
| Sponsor | Boston University Charles River Campus Academic / other |
| Locations | 1 site (Boston, Massachusetts) |
| Status | Recruiting |
| Started | April 12, 2023 |
| Main results expected | July 2027 |
| Study ends | July 2027 |
| Registry record updated | July 31, 2026 |
| Trial ID | NCT05567640 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are English-speaking adults aged 18 or older who have access to the internet.
✕Probably not a fit
Patients who do not have internet access or are under 18 years old may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to enhance the effectiveness of digital mental health interventions for anxiety and depression by utilizing machine learning to develop precision treatment rules. Participants, who are Kaiser Permanente members, will be randomly assigned to one of three established digital programs after completing baseline assessments. The goal is to identify which digital intervention is most suitable for each individual, thereby optimizing user engagement and clinical outcomes. This approach seeks to improve the delivery of mental health care at scale within large healthcare systems.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective digital mental health treatments for individuals suffering from anxiety and depression.
How similar studies have gone: Other studies have shown promise in using machine learning to tailor mental health interventions, indicating that this approach has potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * English-speaking adults * Ages 18 or older * Have a device that can connect to the internet.
Where it's running
-
Center for Anxiety and Related Disorders
Boston, Massachusetts, United States Recruiting
Study contacts
- Principal investigator: Todd Farchione, Ph.D. — Boston University Charles River Campus
- Study coordinator: Todd Farchione, Ph.D.
- Email: tfarchio@bu.edu
- Phone: (617) 353-9610
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
A program to support mental health in American Indian and Alaska Native communities
This study is testing a new program designed to help pregnant women and caregivers in American Indian and Alaska Native communities improve their mental health and coping skills.
-
MAYA mobile CBT for middle-aged and older adults with anxiety or depression
This trial will test whether the MAYA iPhone app helps people age 40 and older with anxiety or depression learn CBT coping skills through brief, twice-weekly sessions.
-
Morning Activation to Boost Mood After Stroke
A six-week behavioral program is tested to see if it helps mood and daily functioning in adults who had a stroke and feel depressed or slow to get going in the morning.
-
Sleep More, Stress Less with Neuralli Mood
This 90-day, open-label study tests whether daily Neuralli Mood capsules can help adults feel less stressed, sleep better, and improve mood and burnout symptoms.
-
Blended Baduanjin and Green Tea Program for Depressive Symptoms in Older Adults
This study tests whether a 12-week combo of gentle Baduanjin exercise and green tea consumption can help reduce depressive symptoms and improve gut health and quality of life in Hong Kong’s community-dwelling adults aged 65–84.
-
Metformin added to antidepressants for depression with obesity in Pakistani adults
This study tests whether adding metformin to antidepressant therapy helps reduce depressive symptoms and BMI in adults with depression and overweight/obesity in Pakistan.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.