Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using machine learning to improve digital mental health interventions

Official title: Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

Run by Boston University Charles River Campus · NCT05567640 · Data updated 2026-11-12

This study is testing if using machine learning can help find the best digital mental health program for people with anxiety and depression to improve their care and results.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1800 (estimated)
SponsorBoston University Charles River Campus
Academic / other
Locations1 site (Boston, Massachusetts)
StatusRecruiting
StartedApril 12, 2023
Main results expectedJuly 2027
Study endsJuly 2027
Registry record updatedJuly 31, 2026
Trial IDNCT05567640 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are English-speaking adults aged 18 or older who have access to the internet.

Probably not a fit

Patients who do not have internet access or are under 18 years old may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to enhance the effectiveness of digital mental health interventions for anxiety and depression by utilizing machine learning to develop precision treatment rules. Participants, who are Kaiser Permanente members, will be randomly assigned to one of three established digital programs after completing baseline assessments. The goal is to identify which digital intervention is most suitable for each individual, thereby optimizing user engagement and clinical outcomes. This approach seeks to improve the delivery of mental health care at scale within large healthcare systems.

Why it matters

Potential benefit: If successful, this study could lead to more personalized and effective digital mental health treatments for individuals suffering from anxiety and depression.

How similar studies have gone: Other studies have shown promise in using machine learning to tailor mental health interventions, indicating that this approach has potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English-speaking adults
* Ages 18 or older
* Have a device that can connect to the internet.

Where it's running

  • Center for Anxiety and Related Disorders
    Boston, Massachusetts, United States
    Recruiting

Study contacts

  • Principal investigator: Todd Farchione, Ph.D. — Boston University Charles River Campus
  • Study coordinator: Todd Farchione, Ph.D.
  • Email: tfarchio@bu.edu
  • Phone: (617) 353-9610

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • MAYA mobile CBT for middle-aged and older adults with anxiety or depression

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    Recruiting Weill Medical College of Cornell University · New York, New York · NCT05754151

  • Morning Activation to Boost Mood After Stroke

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    Recruiting The Hong Kong Polytechnic University · Hong Kong · NCT07719517

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    Recruiting Efforia, Inc · New York, New York · NCT07717385

  • Blended Baduanjin and Green Tea Program for Depressive Symptoms in Older Adults

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    Recruiting Hong Kong Baptist University · Kwun Tong · NCT07687940

  • Metformin added to antidepressants for depression with obesity in Pakistani adults

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    Recruiting at 2 sites Riphah International University · Rawalpindi, Punjab Province and 1 other locations · NCT07654179

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.