Using lung ultrasound to detect fluid overload in severe preeclampsia
Official title: Usefulness of Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia
Run by Saint Thomas Hospital, Panama · NCT07261956 · Data updated 2026-11-12
This project will test whether bedside lung ultrasound can find and monitor fluid buildup (pulmonary edema) in people with severe preeclampsia.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | Women only |
| Enrollment | 202 (estimated) |
| Sponsor | Saint Thomas Hospital, Panama Academic / other |
| Locations | 1 site (Panama City, Provincia de Panamá) |
| Status | Recruiting |
| Started | August 25, 2025 |
| Main results expected | December 31, 2025 |
| Study ends | January 31, 2026 |
| Registry record updated | December 3, 2025 |
| Trial ID | NCT07261956 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Pregnant people between 24 and 41 weeks gestation diagnosed with severe preeclampsia who do not have chronic lung disease or known heart disease, have BMI ≤ 40, and are not in immediate need of delivery.
✕Probably not a fit
Patients with chronic lung disease, known cardiac disease, existing diagnosed pulmonary edema at admission, BMI > 40, or those requiring immediate delivery are excluded and may not benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, longitudinal observational study with a diagnostic validation component enrolling patients with severe preeclampsia. Each participant will receive a clinical exam and an eight-zone lung ultrasound to count B-lines, a sonographic sign of interstitial pulmonary edema. Data will be collected at admission, within 24 hours after delivery, and again 7–10 days postpartum to track changes over time. Lung ultrasound findings will be compared with clinical signs and symptoms of volume overload.
Why it matters
Potential benefit: If successful, this approach could provide a fast, noninvasive way to detect and monitor pulmonary edema, helping clinicians treat fluid overload earlier and potentially reduce maternal complications.
How similar studies have gone: Lung ultrasound and B-line counting have shown promise in detecting pulmonary edema in heart failure and some obstetric cohorts, but evidence specific to severe preeclampsia remains limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Preeclampsia with severe features. * Gestational age 24 weeks - 41 weeks. Exclusion Criteria: * Chronic lung disease. * Known heart disease. * Diagnosis of lung edema at admission * Body mass index \> 40 * Need for immediate delivery
Where it's running
-
Saint Thomas Hospital
Panama City, Provincia de Panamá, Panama Recruiting
Study contacts
- Study coordinator: Anna C Figueroa, MD
- Email: annacfigue@gmail.com
- Phone: +507 69494250
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.