Using light therapy to treat chronic cluster headaches

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the efficacy of light therapy in patients suffering from chronic cluster headaches, a condition that is often challenging to manage. The approach involves using a consumer electronics device, Luminettes®, to deliver light therapy aimed at re-adjusting the chronobiological rhythms associated with this type of headache. Participants will be monitored for the prophylactic effects of this treatment compared to a control group receiving non-therapeutic light emission. The study aims to provide insights into a novel treatment option for this debilitating condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female, of 18 years years old or more;
* Diagnosis of chronic cluster headache according to ICHD-3 criteria;
* Number of seizures during baseline equal to at least 24;
* Stability of prophylactic treatment for at least 1 month and commitment not to change it for the duration of the study;
* Patient affiliated to the French social security system.
* Patient who understands and speaks French correctly;
* Patient who has given free and informed written consent.

Exclusion Criteria:

* Contraindication to the use of light therapy: use of a photosensitizing treatment;
* Ophthalmological history: cataract, macular degeneration, glaucoma, retinitis pigmentosa;
* Patients who work at night;
* Other neurological, psychiatric or developmental pathologies considered incompatible with the study;
* Background treatment of cluster headache with melatonin;
* Persons protected by articles L1121-5, L1121-6 and L1121-8 of the French Public Health Code (pregnant or breast-feeding women, persons deprived of their liberty by judicial decision, socially vulnerable persons, adults incapable or unable to express their consent).

Where it's running

• Hopital La Timone
  Marseille, France Recruiting
• Hôpital de Cimiez
  Nice, France Not yet recruiting

Study contacts

• Study coordinator: Anne DONNET
• Email: anne.donnet@ap-hm.fr
• Phone: +33491384345

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.