Using light therapy to improve healing after tooth extraction in infected gums
Effect of Photodynamic Therapy on Soft Tissue Healing After Tooth Extraction at Sites of Periodontal Infection: a Randomized Controlled Clinical Trial
This study is testing if light therapy can help people with infected gums heal better and feel less pain after having a tooth pulled.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 38 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | The Dental Hospital of Zhejiang University School of Medicine Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT05664087 on ClinicalTrials.gov |
What this trial studies
This study evaluates the impact of photodynamic therapy (PDT) on the healing of soft tissue and bone remodeling following tooth extraction in patients with periodontal infection. Participants will be randomly assigned to either a control group receiving standard tooth extraction or an experimental group receiving PDT to enhance wound cleaning. Healing rates will be assessed at 7 and 14 days post-extraction, along with pain levels measured at various intervals. The study aims to provide insights into the effectiveness of PDT in improving recovery outcomes in dental procedures.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 to 65 with extensive periodontitis and specific extraction needs.
Not a fit: Patients with systemic diseases affecting healing, pregnant or lactating women, and heavy smokers may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to faster and more effective healing for patients undergoing tooth extractions in infected areas.
How similar studies have performed: While the use of photodynamic therapy in dental procedures is gaining interest, this specific application in periodontal infection contexts is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age range from 18 to 65 years old; * Patients with extensive periodontitis of the whole mouth; * There was a deep periodontal pocket with PD≥5mm and at least one adjacent tooth at the extraction site; * Periodontitis was controlled, and the extraction site and adjacent teeth were not in the acute inflammation or infection stage; * The extraction site has a hopeless prognosis or no preservation value, and it is the first and second molars or maxillary wisdom teeth that erupt in a positive position Exclusion Criteria: * pregnant and lactating women; * patients with systemic diseases that may affect the ability of postoperative healing (such as patients with radiotherapy and chemotherapy, history of hematological diseases, and uncontrolled disease) Diabetes mellitus, etc.); * long-term use of drugs known to affect bone metabolism or mucosal healing such as bisphosphonates and non-steroidal anti-inflammatory drugs; * smoking \> 10 cigarettes per day; * root breakage or gingival tear occurred during tooth extraction.
Where this trial is running
Hangzhou, Zhejiang
- The Affiliated Stomatology Hospital of Zhejiang University School of Medicine — Hangzhou, Zhejiang, China (Recruiting)
Study contacts
- Principal investigator: Peihui Ding, Doctor — The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
- Study coordinator: Chen YIxu, master
- Email: kyb@zjkq.com.cn
- Phone: 0571-87219287
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.