Using light therapy to improve gum health in obese patients with periodontitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the effectiveness of adjunct antimicrobial photodynamic therapy (aPDT) in conjunction with scaling and root planing for treating periodontal disease in obese patients. Participants will be divided into two groups, one receiving standard treatment and the other receiving aPDT alongside the standard treatment. The study will assess improvements in periodontal health and analyze changes in the proteomic profile of gingival fluid over a period of 6 months. The goal is to determine if aPDT enhances treatment outcomes compared to traditional methods alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Obesity (grade II and III classified according to Body Mass Index)
* Periodontitis stage II to IV
* Presence of at least 20 teeth excluding 3rd molars.

Exclusion Criteria:

* Smokers
* Alcohol or drugs consumption
* Kidney disorders
* Pregnancy or lactation
* Use of antibiotics at the last 30 days
* Use of drugs that alter periodontal structures as phenytoin or ciclosporin
* Periodontal treatment at the last 6 months

Where it's running

• Bauru School of Dentistry
  Bauru, São Paulo, Brazil Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.