Using light stimulation to enhance vision after optic neuritis in multiple sclerosis patients
Official title: Lichtstimulation Zur Verbesserung Der Sehleistung Bei Patientinnen Und Patienten Mit Multipler Sklerose Nach Sehnerventzündung
Run by Technical University of Munich · NCT06389968 · Data updated 2026-11-12
This study is testing if light stimulation can help improve vision in people with multiple sclerosis who have had optic neuritis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 60 Years |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Technical University of Munich Academic / other |
| Locations | 1 site (Munich, Bavaria) |
| Status | Recruiting |
| Started | August 1, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | November 22, 2024 |
| Trial ID | NCT06389968 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-60 with relapsing-remitting multiple sclerosis who have experienced optic neuritis within the last 1-3 months.
✕Probably not a fit
Patients with conditions such as epilepsy, light-triggered migraines, or significant retinal diseases may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This intervention aims to improve visual function in individuals with multiple sclerosis who have experienced optic neuritis by administering light stimulation. Participants will receive two daily sessions of 80 seconds of light stimulation over 12 days, using a flicker video on a mobile phone. A control group will receive sham stimulation to compare the outcomes. The primary focus is on measuring changes in high-contrast visual acuity, with secondary measures including colored-contrast tests.
Why it matters
Potential benefit: If successful, this approach could significantly enhance visual function in patients recovering from optic neuritis.
How similar studies have gone: While this approach is innovative, similar studies exploring light stimulation for visual function have shown promise, suggesting potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Relapsing remitting multiple sclerosis or clinically isolated syndrome or no indication of chronic inflammatory central nervous system disease * Age 18-60 years * Optic neuritis within 1-3 months Exclusion Criteria: * Epilepsy * Light-triggered migraine * Insufficient vision correction * Retinal disease (glaucoma, macular edema, macula degeneration, ...)
Where it's running
-
Technical University of Munich
Munich, Bavaria, Germany Recruiting
Study contacts
- Study coordinator: Philipp Gulde Gulde, Dr. phil.
- Email: philipp.gulde@tum.de
- Phone: 0049+8928924551
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.