Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

Using light stimulation to enhance vision after optic neuritis in multiple sclerosis patients

Official title: Lichtstimulation Zur Verbesserung Der Sehleistung Bei Patientinnen Und Patienten Mit Multipler Sklerose Nach Sehnerventzündung

Run by Technical University of Munich · NCT06389968 · Data updated 2026-11-12

This study is testing if light stimulation can help improve vision in people with multiple sclerosis who have had optic neuritis.

Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment50 (estimated)
SponsorTechnical University of Munich
Academic / other
Locations1 site (Munich, Bavaria)
StatusRecruiting
StartedAugust 1, 2024
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedNovember 22, 2024
Trial IDNCT06389968 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-60 with relapsing-remitting multiple sclerosis who have experienced optic neuritis within the last 1-3 months.

Probably not a fit

Patients with conditions such as epilepsy, light-triggered migraines, or significant retinal diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This intervention aims to improve visual function in individuals with multiple sclerosis who have experienced optic neuritis by administering light stimulation. Participants will receive two daily sessions of 80 seconds of light stimulation over 12 days, using a flicker video on a mobile phone. A control group will receive sham stimulation to compare the outcomes. The primary focus is on measuring changes in high-contrast visual acuity, with secondary measures including colored-contrast tests.

Why it matters

Potential benefit: If successful, this approach could significantly enhance visual function in patients recovering from optic neuritis.

How similar studies have gone: While this approach is innovative, similar studies exploring light stimulation for visual function have shown promise, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Relapsing remitting multiple sclerosis or clinically isolated syndrome or no indication of chronic inflammatory central nervous system disease
* Age 18-60 years
* Optic neuritis within 1-3 months

Exclusion Criteria:

* Epilepsy
* Light-triggered migraine
* Insufficient vision correction
* Retinal disease (glaucoma, macular edema, macula degeneration, ...)

Where it's running

  • Technical University of Munich
    Munich, Bavaria, Germany
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.