Clinical trial Recruiting at 1 site Interventional Ages 35 to 65

Using laser and air polishing for treating gum disease

Official title: Combined Application of Er:YAG Laser and Sub-gingival Air Polishing Powder in Treatment of Periodontitis: A Split-mouth, Randomized Controlled Trial

Run by Beijing Chao Yang Hospital · NCT06574802 · Data updated 2026-11-12

This study tests if using a laser along with air polishing can help people with gum disease feel better compared to just using the laser alone.

Quick facts

Study typeInterventional
Ages35 Years to 65 Years
SexAll
Enrollment60 (estimated)
SponsorBeijing Chao Yang Hospital
Academic / other
Locations1 site (Beijing, Beijing Municipality)
StatusRecruiting
StartedSeptember 4, 2024
Main results expectedDecember 2026
Study endsDecember 2027
Registry record updatedFebruary 7, 2025
Trial IDNCT06574802 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 35-65 with generalized stage II or III periodontitis and a minimum of 20 teeth.

Probably not a fit

Patients who are pregnant, have diabetes, or have received recent periodontal treatment may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of combining Er:YAG laser treatment with sub-gingival air polishing in patients with generalized stage II or III periodontitis. It employs a split-mouth design where two quadrants of the mouth are treated differently: one with the combined approach and the other with laser treatment alone. Clinical evaluations will be conducted at multiple time points over two years to assess the outcomes of both treatment methods in a Chinese population.

Why it matters

Potential benefit: If successful, this approach could enhance the effectiveness of periodontal treatment and improve patient outcomes in managing gum disease.

How similar studies have gone: While there have been studies on laser treatments for periodontal disease, the specific combination of Er:YAG laser and air polishing is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 1\) aged 35-65 years old, in good systemic healthy;
* 2\) clinically diagnosed with generalized stage Ⅱ or stage Ⅲ periodontitis;
* 3\) a minimum of 20 teeth

Exclusion Criteria:

* 1\) pregnancy or recent pregnancy plans;
* 2\) had received periodontal treatment within the previous 6 months;
* 3\) taken antibiotics within the previous 3 months;
* 4\) had diabetes;
* 5\) obvious malocclusion, history of orthodontic treatment, or a habit of mouth breathing.

Where it's running

  • Beijing Chao Yang Hospital
    Beijing, Beijing Municipality, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.