Clinical trial Recruiting at 1 site Interventional Ages 20 and up

Using laser acupuncture to help prevent chronic migraines

Official title: Enhancing Chronic Migraine Preventive Therapy: Laser Acupuncture as an Add-On Treatment for Patients With Unsatisfactory Pharmacological Effect, a Pilot Randomized Controlled Trial

Run by Taichung Veterans General Hospital · NCT06219694 · Data updated 2026-11-12

This study is testing if laser acupuncture can help people with chronic migraines have fewer headache days and feel better overall.

Quick facts

Study typeInterventional
Ages20 Years and up
SexAll
Enrollment60 (estimated)
SponsorTaichung Veterans General Hospital
Academic / other
Locations1 site (Taichung, Xitun District)
StatusRecruiting
StartedJanuary 1, 2022
Main results expectedMay 4, 2022
Study endsDecember 1, 2025
Registry record updatedNovember 20, 2025
Trial IDNCT06219694 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 20 years old with chronic migraines who have not found relief from current pharmacological treatments.

Probably not a fit

Patients who have received laser acupuncture or traditional acupuncture prior to the study may not benefit from this trial.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the efficacy and safety of laser acupuncture as an add-on preventive therapy for chronic migraine patients. Participants aged over 20 with a history of chronic migraines will be randomly assigned to receive either laser acupuncture or a sham treatment. The study will evaluate changes in monthly migraine days, medication usage, and psychological assessments over a six-month period, followed by an additional three months for the sham group after receiving the treatment. The goal is to determine if laser acupuncture can effectively reduce migraine frequency and improve overall patient well-being.

Why it matters

Potential benefit: If successful, this treatment could provide a non-invasive option for chronic migraine prevention, potentially reducing reliance on pharmacological interventions.

How similar studies have gone: While acupuncture has been established as a treatment for migraines, the specific efficacy of laser acupuncture remains inconclusive, making this approach somewhat novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients aged above 20 years old and had CM managed pharmacologically, including preventive and/or acute migraine medications, and in addition, those who had refused preventive agent despite recommendation of the neurologist;
* patients who had unsatisfactory effect of current pharmacological treatments, defined as they self-reported
* patients who had a minimum of one-year history of migraine with or without aura.

Exclusion Criteria:

* patients who had received another LA therapy or traditional acupuncture at baseline
* migraine onset after the age of 50
* cognitive or psychological impairment interfering with the participant's ability to receive LA protocol and describe symptoms
* patients with missing data at baseline or during the follow-up period.

Where it's running

  • Taichung Veterans General Hospital
    Taichung, Xitun District, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.