Using laser acupuncture to help prevent chronic migraines
Official title: Enhancing Chronic Migraine Preventive Therapy: Laser Acupuncture as an Add-On Treatment for Patients With Unsatisfactory Pharmacological Effect, a Pilot Randomized Controlled Trial
Run by Taichung Veterans General Hospital · NCT06219694 · Data updated 2026-11-12
This study is testing if laser acupuncture can help people with chronic migraines have fewer headache days and feel better overall.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Taichung Veterans General Hospital Academic / other |
| Locations | 1 site (Taichung, Xitun District) |
| Status | Recruiting |
| Started | January 1, 2022 |
| Main results expected | May 4, 2022 |
| Study ends | December 1, 2025 |
| Registry record updated | November 20, 2025 |
| Trial ID | NCT06219694 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 20 years old with chronic migraines who have not found relief from current pharmacological treatments.
✕Probably not a fit
Patients who have received laser acupuncture or traditional acupuncture prior to the study may not benefit from this trial.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the efficacy and safety of laser acupuncture as an add-on preventive therapy for chronic migraine patients. Participants aged over 20 with a history of chronic migraines will be randomly assigned to receive either laser acupuncture or a sham treatment. The study will evaluate changes in monthly migraine days, medication usage, and psychological assessments over a six-month period, followed by an additional three months for the sham group after receiving the treatment. The goal is to determine if laser acupuncture can effectively reduce migraine frequency and improve overall patient well-being.
Why it matters
Potential benefit: If successful, this treatment could provide a non-invasive option for chronic migraine prevention, potentially reducing reliance on pharmacological interventions.
How similar studies have gone: While acupuncture has been established as a treatment for migraines, the specific efficacy of laser acupuncture remains inconclusive, making this approach somewhat novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients aged above 20 years old and had CM managed pharmacologically, including preventive and/or acute migraine medications, and in addition, those who had refused preventive agent despite recommendation of the neurologist; * patients who had unsatisfactory effect of current pharmacological treatments, defined as they self-reported * patients who had a minimum of one-year history of migraine with or without aura. Exclusion Criteria: * patients who had received another LA therapy or traditional acupuncture at baseline * migraine onset after the age of 50 * cognitive or psychological impairment interfering with the participant's ability to receive LA protocol and describe symptoms * patients with missing data at baseline or during the follow-up period.
Where it's running
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Taichung Veterans General Hospital
Taichung, Xitun District, Taiwan Recruiting
Study contacts
- Study coordinator: ChiSheng Wang, M.D
- Email: sam7227632@gmail.com
- Phone: +886933375721
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.