Using ketamine to manage pain after hemorrhoid surgery
Intra-operative Use of Ketamine for Post-Operative Analgesia in Patients Undergoing Hemorrhoidectomy: A Prospective, Randomized Controlled Trial.
This study is testing if using ketamine during hemorrhoid surgery can help reduce pain afterwards for patients with severe hemorrhoids.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | University of Oklahoma Academic / other |
| Locations | 1 site (Oklahoma City, Oklahoma) |
| Trial ID | NCT04248205 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of ketamine as a pain management option for patients undergoing hemorrhoidectomy for Grade III or IV hemorrhoids. Approximately 100 participants will be randomly assigned to receive either an intraoperative ketamine infusion or standard anesthesia without ketamine. The study will assess post-operative pain levels using numeric rating scales and follow-up evaluations at two weeks post-surgery. All participants will receive standardized post-operative care and pain management instructions.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-100 who are scheduled for a hemorrhoidectomy due to Grade III or IV hemorrhoids.
Not a fit: Patients who cannot undergo general anesthesia or have contraindications to hemorrhoidectomy will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve post-operative pain management for patients undergoing hemorrhoidectomy.
How similar studies have performed: Previous studies have shown promising results with ketamine for pain management in various surgical settings, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18-100 * Undergoing a hemorrhoidectomy for Grade III or IV hemorrhoids. Exclusion Criteria: * Inability to undergo general anesthesia * Contraindications to hemorrhoidectomy * History of schizophrenia or other hallucinatory psychiatric illnesses * History of psychosis * Chronic narcotic usage defined as either having a pain contract with a pain management specialist and no narcotic usage for one month prior to hemorrhoidectomy.
Where this trial is running
Oklahoma City, Oklahoma
- University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States (Recruiting)
Study contacts
- Principal investigator: Steven N Carter, MD — University of Oklahoma
- Study coordinator: Steven N Carter, MD
- Email: steven-carter@ouhsc.edu
- Phone: 405-271-8001
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.