Using IVC collapsibility and diameters to predict blood pressure drops during hemodialysis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a multicenter prospective observational study that records inferior vena cava (IVC) measurements once, at one hour after dialysis start, to see how well IVCCI, IVCmax, and IVCmin predict intradialytic hypotension. Ultrasound measurements will be collected at participating hospitals in Wuhu and linked to blood pressure readings and dialysis session data. Eligible participants are adults with end-stage renal disease on maintenance hemodialysis for at least three months, while patients with acute kidney injury, severe cardiac disease, hemodynamic instability, or barriers to ultrasound are excluded. The study uses noninvasive bedside ultrasonography and correlational analysis to determine whether a single-timepoint IVC metric can identify patients at higher risk of hypotension during dialysis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years or older.
* Diagnosed with end-stage renal disease (ESRD).
* Undergoing regular hemodialysis for at least three months.

Exclusion Criteria:

* Pregnant or breastfeeding women.
* Hemodynamically unstable patients or those requiring vasopressor support.
* Patients with severe cardiac conditions, including congestive heart failure -classified as NYHA Class III-IV or severe valvular disease.
* Patients with known allergies to dialysis filters.
* Dialysis sessions terminated for reasons unrelated to hypotension (e.g., technical issues, patient request).
* Patients who withdraw informed consent during the study.
* Use of antihypertensive medications during dialysis sessions.
* Inability to undergo ultrasound assessment due to factors such as severe obesity or wounds obstructing access.

Where it's running

• The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)
  Wuhu, Anhui, China Recruiting

Study contacts

• Study coordinator: Qiancheng Xu
• Email: qianchengxu@wnmc.edu.cn
• Phone: 86-18297529106

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.