Clinical trial Recruiting at 1 site Interventional Ages 20 to 70

Using internal jugular vein ultrasound to guide fluids during abdominal surgery

Official title: Effect of Intraoperative Fluid Management Guided by Respiratory Variations of Internal Jugular Vein on Postoperative Complications in Abdominal Surgeries: A Prospective Randomized Controlled Trial

Run by Suez Canal University · NCT07041021 · Data updated 2026-11-12

This trial will try using ultrasound measurements of breathing-related changes in the internal jugular vein to guide how much fluid adults aged 20–70 receive during abdominal surgery and see if that lowers postoperative complications.

Quick facts

Study typeInterventional
Ages20 Years to 70 Years
SexAll
Enrollment84 (estimated)
SponsorSuez Canal University
Academic / other
Locations2 sites (Ismailia, Ismailia Governorate and 1 other locations)
StatusRecruiting
StartedJuly 15, 2025
Main results expectedMay 2026
Study endsMay 2026
Registry record updatedApril 7, 2026
Trial IDNCT07041021 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20–70 with ASA physical status I–II and normal renal function scheduled for abdominal surgery under general anesthesia, without pre-existing cardiac, renal, or respiratory disease, coagulopathy, or internal jugular vein thrombosis.

Probably not a fit

Patients with significant cardiac, renal, or respiratory disease, coagulopathy, internal jugular vein thrombosis, ASA III or higher, or those outside the 20–70 age range are unlikely to be eligible or to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults undergoing abdominal surgery under general anesthesia are randomized to receive intraoperative fluid therapy guided by respiratory variation of the internal jugular vein measured by ultrasound or to receive standard fluid therapy. A trained anesthesiologist will obtain left IJV M-mode measurements at the cricoid level using a Philips CX50 and calculate IJV respiratory variation from three respiratory cycles to guide fluid decisions. The ultrasound operator is not involved in anesthesia management and is separated from monitors to maintain blinding of hemodynamic data while clinicians follow the allocated fluid protocol intraoperatively. Postoperative complications and length of hospital stay are compared between groups to determine whether IJV-guided fluid management reduces adverse events.

Why it matters

Potential benefit: If successful, this approach could reduce postoperative complications and shorten hospital stay by tailoring intraoperative fluids to each patient's volume status.

How similar studies have gone: Physiologic and small clinical studies using respiratory variation of central or inferior vena cava veins support the concept of dynamic venous indices to guide fluids, but large randomized trials showing reduced postoperative complications specifically using IJV variation are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients' American Society of Anesthesiologists physical status (ASA) is I and II.
2. The target age group is 20 to 70 years old.
3. Patients scheduled for abdominal surgery under general anesthesia with normal renal function.

Exclusion Criteria:

1. Refusal of the procedure or participation in the study.
2. Coagulopathy.
3. Pre-existing cardiac, renal, and respiratory diseases. 4-Internal jugular vein thrombosis

Where it's running

  • Suez Canal University Hospitals
    Ismailia, Egypt
    Recruiting
  • Suez Canal University Hospitals
    Ismailia, Ismailia Governorate, Egypt
    Not yet recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.