Using incentive spirometry to help lung cancer patients during treatment
Incentive Spirometry for Respiratory Enhancement Pilot Clinical Trial in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy
This study is testing whether using an incentive spirometer can help lung cancer patients breathe better and feel healthier during and after their treatment.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | The Cooper Health System Academic / other |
| Drugs / interventions | chemotherapy, immunotherapy, radiation |
| Locations | 1 site (Camden, New Jersey) |
| Trial ID | NCT06688422 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates whether using an incentive spirometer can reduce lung complications in patients with advanced lung cancer undergoing concurrent chemotherapy and radiation therapy. Participants will use the spirometer to encourage deep breathing multiple times an hour while awake, both during treatment and for up to three months afterward. The study aims to assess the impact of this non-pharmacological intervention on the incidence of pneumonitis and overall quality of life, with evaluations conducted at various intervals. By comparing outcomes, researchers hope to determine the effectiveness of incentive spirometry in improving patient well-being during and after cancer treatment.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a confirmed diagnosis of advanced non-small-cell lung cancer and a good performance status.
Not a fit: Patients with previous lung or thoracic surgery, those using home oxygen prior to enrollment, or those with active respiratory infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce lung problems and enhance the quality of life for lung cancer patients undergoing treatment.
How similar studies have performed: While incentive spirometry has shown promise in postoperative settings, its application in oncology is less explored, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Confirmed diagnosis of advanced non-small-cell lung cancer * Performance status (ECOG 0-1) * Eligible for concurrent chemotherapy and radiation * 18 years or older Exclusion Criteria: * Previous lung or thoracic surgery * Enrollment in another pulmonary intervention trial * Home oxygen usage prior to enrolment * Radiological evidence of pleural effusion, pneumothorax, bullous emphysema, - or pneumonitis on staging imaging * Presence of active respiratory tract infection * Uncontrolled nausea and vomiting * Prior exposure to drugs such as amiodarone, bleomycin, or immunotherapy * Inability or unwillingness of individual to give written informed consent
Where this trial is running
Camden, New Jersey
- MD Anderson Cancer Center at Cooper — Camden, New Jersey, United States (Recruiting)
Study contacts
- Study coordinator: Veli Bakalov, MD
- Email: bakalov-veli@cooperhealth.edu
- Phone: 856-735-6100
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.