Using ICG Angiography to Detect Parathyroid Glands During Thyroid Surgery
Contribution of Indocyanine Green Angiography in the Detection of Parathyroids and the Prevention of Hypoparathyroidism Post Total Thyroidectomy
This study is testing if using a special imaging technique during thyroid surgery can help doctors find and protect the parathyroid glands to reduce the risk of complications for patients.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 242 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Brest Academic / other |
| Locations | 1 site (Brest) |
| Trial ID | NCT04785443 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the use of indocyanine green (ICG) angiography during total thyroidectomy to improve the detection of parathyroid glands and reduce the risk of postoperative hypoparathyroidism. Hypoparathyroidism is a common complication that can lead to significant quality of life deterioration if it becomes permanent. By utilizing ICG angiography, the study aims to enhance the preservation of parathyroid glands during surgery, potentially decreasing the incidence of this complication. The trial will compare outcomes between patients receiving ICG angiography and a control group.
Who should consider this trial
Good fit: Ideal candidates for this study are patients scheduled to undergo total thyroidectomy who can provide informed consent.
Not a fit: Patients who have previously undergone thyroid or parathyroid surgery or those with known allergies to ICG may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the rates of postoperative hypoparathyroidism, improving patient outcomes and quality of life.
How similar studies have performed: Previous studies have shown promising results with the use of ICG angiography in similar surgical contexts, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient having to undergo a total thyroidectomy * Signed consent * Patient beneficiary of a social security regimen Exclusion Criteria: * Minor patient under 18 years old * Major patient protected by law or unable to give informed consent * Pregnant or breastfeeding woman * Thyroidectomy totalization * History of thyroid or parathyroid surgery * Participation refusal * Known allergy to ICG * Woman of child-bearing age not using adequate method of contraception
Where this trial is running
Brest
- CHRU de Brest — Brest, France (Recruiting)
Study contacts
- Principal investigator: Jean-Christophe LECLERE, PhD — CHRU de Brest
- Study coordinator: Jean-Christophe LECLERE, PhD
- Email: jean-christophe.leclere@chu-brest.fr
- Phone: 0298223630
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.