Using hyperbaric oxygen therapy to speed up recovery after ACL surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of hyperbaric oxygen therapy (HBOT) in accelerating recovery following anterior cruciate ligament reconstruction (ACLR). ACL injuries are common among athletes, and the recovery process can take around eight months. The research aims to determine if HBOT can enhance healing and reduce recovery time based on previous findings in animal studies and limited human trials. Participants will undergo HBOT as part of their rehabilitation to assess improvements in recovery metrics.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Subjects willing and able to read, understand and sign an informed consent
2. Age 18-45
3. Anterior cruciate ligament tear for reconstruction (with or without meniscal repair).

Exclusion Criteria:

1. Inability to attend scheduled clinic visits and/or comply with the study protocol
2. Additional injury
3. An inability to perform MRI.
4. Active malignancy
5. Chest pathology incompatible with pressure changes (including active asthma)
6. Ear or sinus pathology incompatible with pressure changes
7. History of epilepsy
8. Claustrophobia
9. Previous knee surgery
10. Participation in another study

Where it's running

• The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center (Assaf Harofeh)
  Zrifin, Israel Recruiting

Study contacts

• Principal investigator: Shai a Efrati, MD — Asaf-Harofhe MC
• Study coordinator: Shai a Efrati, MD
• Email: efratishai@outlook.com
• Phone: 972549212866

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Analgesic effects of adding BiFeS block to adductor canal block after ACL reconstruction

  This study tests whether adding a BiFeS block to the standard adductor canal block provides better pain relief after ACL reconstruction.

  Recruiting Ankara Etlik City Hospital · Ankara · NCT07859397

• Donor ankle sensorimotor recovery after ACL reconstruction with a peroneus longus graft

  This study tests how the donor ankle recovers sensorimotor function after ACL reconstruction using a peroneus longus tendon autograft in adults 18–55.

  Recruiting Gazi University · Çankaya, Ankara · NCT07762989

• ACL Tear: Reconstruction vs Primary Repair outcomes after surgery

  This study tests how patients who had ACL reconstruction compare with those who had arthroscopic primary ACL repair in terms of strength, endurance, fatigue, knee stability, and function after surgery.

  Recruiting Gazi University · Ankara, Çankaya · NCT07318272

• Fractal versus steady visual walking cues after ACL reconstruction

  This tests whether fractal (variable) visual walking cues or steady metronome-like cues help athletes who had ACL reconstruction walk with steadier, safer patterns.

  Recruiting Egas Moniz - Cooperativa de Ensino Superior, CRL · Almada, Monte de Caparica · NCT07243535

• Brain-computer visualization training to improve muscle activation after orthopedic surgery

  This tests whether adding EEG-based neurofeedback visualization to usual physical therapy helps adults recovering from ACL, hip, or knee surgery activate their muscles better and speed recovery.

  Recruiting Phase 2 Rush University Medical Center · Chicago, Illinois · NCT07020312

• Eccentric training for rehabilitation after ACL surgery

  This study is testing if a special type of exercise called eccentric training helps people recover better after ACL surgery compared to regular rehab exercises.

  Recruiting Federal University of Health Science of Porto Alegre · Veranópolis, Rio Grande do Sul and 1 other locations · NCT06905691

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.