Using Huaier granules to prevent colorectal cancer recurrence after surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates the efficacy and safety of Huaier granules in preventing the recurrence and metastasis of colorectal cancer in patients who have undergone radical surgery. It is a multisite, open-label, prospective study involving patients diagnosed with stage IIB, IIC, and III colorectal cancer. Participants will be monitored for their health outcomes following treatment with Huaier granules within two months post-surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Males or females ages 18-75 years;
2. The first time to the therapy of patients who received the radical surgery within two months, Postoperative histopathology confirms the diagnosis of colorectal cancer with stage IIB, IIC and III ( TNM classification)
3. ECOG score of 0-2;
4. No history of malignant tumors;
5. The patients are volunteered for the study, sign informed consent form and cooperate with Investigator to collect data.

Exclusion Criteria:

1. Patients have basic diseases including heart diseases, cerebrovascular disease, lung disease, severe hypertension or diabetes with poor glycemic control;
2. confirmed infections after surgery ;
3. Patients who have post-surgery complications or who are currently under the influence of the radical surgery for colorectal cancer;
4. Being infected with syphilis or with other blood-borne infectious diseases;
5. Pregnancy or lactation; or women of childbearing potential not using contraception;
6. Patients who have taken Traditional Chinese Medicines with efficacy and indications similar to that of Huaier granule - including, but not limited to, compound Banmao capsule., Huachansu capsule, Kangai Injection and Pingxiao tablets;
7. Patients who are suffering from mental illness or Conditions that are considered not suitable for this study investigators.

Where it's running

• The Fourth Hospital of Hebei Medical University
  Shijiazhuang, Hebei, China Recruiting
• The First Clinical Hospital affiliated to Harbin Medical University
  Harbin, Heilongjiang, China Recruiting
• The Second Affiliated Hospital of Harbin Medical University
  Harbin, Heilongjiang, China Recruiting
• Hubei Cancer Hospita
  Wuhan, Hubei, China Recruiting
• Union Hospital Tongji College Huazhong University of Science and Technology
  Wuhan, Hubei, China Recruiting
• Hunan Provincial People's Hospital
  Changsha, Hunan, China Recruiting

Study contacts

• Principal investigator: Xishan Wang, Professor — Cancer Institute and Hospital, Chinese Academy of Medical Sciences
• Study coordinator: Xishan Wang, Professor
• Email: wangxishanzy@sina.com
• Phone: +0086-13552367779

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.