Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Using high-flow nasal oxygen for preoxygenation in emergency surgery patients with full stomachs

Official title: Research on Pre-Anesthetic Blood Oxygenation Effect of High-Flow Nasal Oxygen for Emergency Surgery Patients With Full Stomachs

Run by Vietnam Military Medical University · NCT06879600 · Data updated 2026-11-12

This study is testing if high-flow nasal oxygen can help emergency surgery patients with full stomachs breathe better before anesthesia compared to using a regular face mask.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorVietnam Military Medical University
Academic / other
Locations1 site (Viet Tri, Phu Tho)
StatusRecruiting
StartedJuly 19, 2023
Main results expectedDecember 15, 2026
Study endsDecember 31, 2026
Registry record updatedMarch 17, 2025
Trial IDNCT06879600 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult emergency surgical patients at risk of gastric fullness requiring endotracheal intubation.

Probably not a fit

Patients with predicted difficult airways, respiratory diseases, or those who cannot achieve a proper mask seal may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of high-flow nasal oxygen (HFNO) therapy for preoxygenation in adult patients undergoing emergency surgery with full stomachs. Participants will be randomly assigned to either receive HFNO or traditional face mask preoxygenation before anesthesia induction. The study aims to assess whether HFNO can improve oxygenation and reduce the risk of hypoxemia during the critical period of intubation. The trial is conducted at a single center, focusing on patients classified as ASA I or II who are at risk of gastric fullness.

Why it matters

Potential benefit: If successful, this approach could enhance patient safety by reducing the risk of hypoxemia during anesthesia induction in emergency surgeries.

How similar studies have gone: While the use of HFNO in various settings has shown promise, this specific application in emergency surgery patients with full stomachs is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Emergency surgical patients at risk of gastric fullness requiring endotracheal intubation.
* Patients aged 18 years or older.
* Health status classified as ASA I or II.
* Mallampati classification I or II.

Exclusion Criteria:

* Patients with a predicted difficult airway, facial deformities, or an inability to achieve a proper mask seal.
* Patients with respiratory diseases.
* Pregnant patients.
* Patients allergic to anesthesia or resuscitation drugs.
* Patients who do not consent to participate in the study.

Where it's running

  • Department of Anesthesia, Phu Tho General Hospital
    Viet Tri, Phu Tho, Vietnam
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.