Using high-flow nasal oxygen for preoxygenation in emergency surgery patients with full stomachs
Research on Pre-Anesthetic Blood Oxygenation Effect of High-Flow Nasal Oxygen for Emergency Surgery Patients With Full Stomachs
This study is testing if high-flow nasal oxygen can help emergency surgery patients with full stomachs breathe better before anesthesia compared to using a regular face mask.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Vietnam Military Medical University Academic / other |
| Locations | 1 site (Viet Tri, Phu Tho) |
| Trial ID | NCT06879600 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of high-flow nasal oxygen (HFNO) therapy for preoxygenation in adult patients undergoing emergency surgery with full stomachs. Participants will be randomly assigned to either receive HFNO or traditional face mask preoxygenation before anesthesia induction. The study aims to assess whether HFNO can improve oxygenation and reduce the risk of hypoxemia during the critical period of intubation. The trial is conducted at a single center, focusing on patients classified as ASA I or II who are at risk of gastric fullness.
Who should consider this trial
Good fit: Ideal candidates are adult emergency surgical patients at risk of gastric fullness requiring endotracheal intubation.
Not a fit: Patients with predicted difficult airways, respiratory diseases, or those who cannot achieve a proper mask seal may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance patient safety by reducing the risk of hypoxemia during anesthesia induction in emergency surgeries.
How similar studies have performed: While the use of HFNO in various settings has shown promise, this specific application in emergency surgery patients with full stomachs is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Emergency surgical patients at risk of gastric fullness requiring endotracheal intubation. * Patients aged 18 years or older. * Health status classified as ASA I or II. * Mallampati classification I or II. Exclusion Criteria: * Patients with a predicted difficult airway, facial deformities, or an inability to achieve a proper mask seal. * Patients with respiratory diseases. * Pregnant patients. * Patients allergic to anesthesia or resuscitation drugs. * Patients who do not consent to participate in the study.
Where this trial is running
Viet Tri, Phu Tho
- Department of Anesthesia, Phu Tho General Hospital — Viet Tri, Phu Tho, Vietnam (Recruiting)
Study contacts
- Study coordinator: Hong Bui Minh, M.D
- Email: Drhong88gmhs@gmail.com
- Phone: 0971025586
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.