Using high-definition electromyography to diagnose sarcopenia in older adults
Official title: HD-sEMG Markers of Sarcopenia
Run by Assistance Publique - Hôpitaux de Paris · NCT04987814 · Data updated 2026-11-12
This study is testing a new way to diagnose muscle loss in older adults using a special technology to see if it can help identify those who may have sarcopenia.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 75 Years and up |
| Sex | All |
| Enrollment | 175 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 6 sites (Ivry-sur-Seine and 5 other locations) |
| Status | Recruiting |
| Started | May 18, 2022 |
| Main results expected | November 18, 2026 |
| Study ends | December 18, 2026 |
| Registry record updated | May 23, 2025 |
| Trial ID | NCT04987814 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals aged 75 years and older who are hospitalized and suspected of having sarcopenia.
✕Probably not a fit
Patients with a BMI of 30 kg/m2 or higher, untreated/unbalanced endocrinological conditions, or severe cognitive disorders are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot project aims to explore the use of high-definition surface electromyography (HD-sEMG) technology for diagnosing sarcopenia, a condition characterized by the loss of muscle mass and function in older adults. The study will include 50 participants aged 75 and over who are hospitalized and suspected of having sarcopenia, as indicated by a score of 4 or higher on the SARC-F screening questionnaire. Participants will undergo assessments of body composition using dual X-ray absorptiometry (DEXA) and muscular strength evaluations. The study is designed to develop a new diagnostic method that combines both morphological and functional assessments of skeletal muscle.
Why it matters
Potential benefit: If successful, this study could lead to a more accurate and accessible method for diagnosing sarcopenia, improving patient outcomes and management.
How similar studies have gone: While the use of HD-sEMG for diagnosing sarcopenia is a novel approach, similar studies have shown promise in using advanced imaging and functional assessments for muscle evaluation.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient aged 75 years and over * Score ≥4 on the SARC-F screening questionnaire * Enrolled in a social security plan (no AME) * Informed and consenting patient Exclusion Criteria: * BMI ≥30 kg/m2 * Untreated/unbalanced endocrinological pathology * Myopathy * Inflammatory or autoimmune pathology * Severe psychiatric pathology or severe cognitive disorders that do not allow the performance of examinations * Patients who are dependent for all acts of daily life * Patients with a very short life expectancy * Recent fracture or trauma of the lower limbs preventing dynamic measurement of HD-sEMG recording * Bilateral hip prosthesis * Skin problem that may interfere with the recording of surface EMG activity * Patient under guardianship / curatorship
Where it's running
-
Service de gériatrie aigue polyvalente (GAP)
Ivry-sur-Seine, France Recruiting -
Service de soins de suite et de réadaptation Gériatrique 1
Ivry-sur-Seine, France Recruiting -
Service de soins de suite et de réadaptation gériatrique 2
Ivry-sur-Seine, France Recruiting -
Service de soins de suite et de réadaptation -Plaies et cicatrisation
Paris, France Recruiting -
Service de soins de suite et de réadaptation Gériatrique Hôpital Rothschild
Paris, France Recruiting -
Unité d'Explorations fonctionnelles du sujet âgé, Hôpital Charles Foix
Ivry-sur-Seine, France Not yet recruiting
Study contacts
- Principal investigator: Kiyoka KINUGAWA, MD PhD — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Kiyoka KINUGAWA, MD PhD
- Email: kiyoka.kinugawa@aphp.fr
- Phone: +331 49 59 47 53
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Sarcopenia in Patients After Cardiac Surgery
This observational study tests how common sarcopenia is after cardiac surgery and whether current care helps improve muscle mass and function.
-
Bone marrow mesenchymal stem cell injection for sarcopenia
This study tests whether CG-BM1, a stem cell injection, can be safely given to adults with sarcopenia to see if it helps improve muscle health.
-
GLP-1 receptor agonist use and muscle health in adults with obesity without diabetes
This study tests whether GLP-1 receptor agonists affect muscle mass and strength in adults with obesity who don’t have diabetes.
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Sarcopenia and Epidural Steroid Injections in Lumbar Spinal Stenosis
We’re testing how sarcopenia relates to pain, function, and quality of life after a routine interlaminar epidural steroid injection in people with lumbar spinal stenosis.
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Using Multimodal Ultrasound to Check Muscle Mass in Metabolic Disease Patients
This study tests whether a multimodal ultrasound approach can accurately measure muscle mass in people with metabolic syndrome, obesity, sarcopenia, or type 2 diabetes.
-
Lower-limb rehabilitation robot training with nutrition education for sarcopenia
In adults aged 60 and older with sarcopenia, this study tests whether adding robot-assisted leg training to nutrition education can improve muscle mass and walking ability compared with usual care.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.