Using GnRH for support during IVF cycles
GnRH for Luteal Support in IVF/ICSI/FET Cycles
PHASE4 · University Reproductive Associates · NCT02357654
This study is testing if giving a hormone called GnRH during IVF can help women under 40 have a better chance of getting pregnant and having a baby.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 350 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | Female |
| Sponsor | University Reproductive Associates (other) |
| Locations | 1 site (Hasbrouck Heights, New Jersey) |
| Trial ID | NCT02357654 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the use of GnRH agonists to provide additional support for the endometrium during in vitro fertilization (IVF) cycles. The study aims to determine whether a single administration of GnRH around the time of embryo transfer can enhance implantation and live birth rates compared to a placebo. Women under 40 undergoing IVF or frozen embryo transfers will be eligible to participate. The trial will assess the effectiveness of this intervention in improving reproductive outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are women under 40 years old who are undergoing IVF, ICSI, or frozen embryo transfers.
Not a fit: Patients who are undergoing day 3 embryo transfers may not receive benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve implantation rates and live birth outcomes for women undergoing IVF.
How similar studies have performed: Other studies have shown promising results with similar approaches, indicating potential for success in this trial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * women undergoing IVF/ICSI or frozen embryo transfers (FET) that less than 40 years old. Exclusion Criteria: * day 3 transfers
Where this trial is running
Hasbrouck Heights, New Jersey
- University Reproductive Associates — Hasbrouck Heights, New Jersey, United States (RECRUITING)
Study contacts
- Principal investigator: Peter G McGovern, MD — Rutgers University
- Study coordinator: Peter G McGovern, MD
- Email: mcgovepg@gmail.com
- Phone: 201-288-6330
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Infertility