Using fecal calprotectin to predict esophageal varices in cirrhotic patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the accuracy of fecal calprotectin levels in predicting the presence and grading of esophageal varices in patients with liver cirrhosis. Researchers will compare fecal calprotectin levels among cirrhotic patients with and without esophageal varices, as well as healthy subjects. The study will also assess various non-invasive scoring systems, including APRI, FIB-4, ALBI, PALBI, and PSR scores, to determine their effectiveness in predicting esophageal varices. Participants will undergo clinical assessments, laboratory tests, and endoscopic evaluations to classify the varices.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years
* Liver cirrhosis

Exclusion Criteria:

* Patients aged \< 18 years.
* Inflammatory bowel disease.
* Infectious gastroenteritis.
* Malignancy.
* Patients on proton pump inhibitors or NSAID.
* Patients with spontaneous bacterial peritonitis.
* Patients with hepatic encephalopathy.
* Unwilling to participate in our study.

Where it's running

• Tanta University Hospitals
  Tanta, Gharbyea, Egypt Recruiting

Study contacts

• Principal investigator: Rania M Elkafoury, MD — Tropical medicine and infectious diseases Department, Faculty of Medicine, Tanta University
• Study coordinator: Rania M Elkafoury, MD
• Email: rania.elkafoury@med.tanta.edu.eg
• Phone: +201004672358

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.