Using ex-vivo lung perfusion for lung transplantation
Observational Study on the Clinical Use of Ex Vivo Lung Perfusion (XPS™) for Lung Transplantation
This study is testing if a new method for keeping lungs healthy outside the body can improve outcomes for people receiving lung transplants.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hannover Medical School Academic / other |
| Locations | 1 site (Hannover) |
| Trial ID | NCT06795516 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on the clinical application of ex-vivo lung perfusion (XPS™) in lung transplantation. It involves the collection, storage, and processing of patient data to analyze outcomes related to the use of this technology. The study aims to assess the effectiveness and safety of the XPS™ system in improving lung transplant results. Participants will be evaluated based on clinical assessments and visual inspections of the organs.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who are receiving lung transplants assessed using the XPS™ system.
Not a fit: Patients who do not meet the standard donor assessment criteria or whose lung assessment does not satisfy the transplanting surgeon will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance the viability and outcomes of lung transplants for patients.
How similar studies have performed: Other studies have shown promise in using ex-vivo lung perfusion techniques, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Min Age 18 years * Acceptance of the organ using the XPS™ ex vivo lung perfusion system is made by the center based on clinical assessment and visual inspection Exclusion Criteria: * The usual criteria for the assessment of donors apply * The transplanting surgeon is not satisfied with the lung assessment on the XPS™ according to clinical criteria
Where this trial is running
Hannover
- Hannover Medical School, Department of Cardiothoracic, Transplant and Vascular Surgery — Hannover, Germany (Recruiting)
Study contacts
- Principal investigator: Fabio Ius, Prof. Dr. — Hannover Medical School
- Study coordinator: Fabio Ius, Prof. Dr.
- Email: ius.fabio@mh-hannover.de
- Phone: +49 511-532-2125
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.