Using Erector Spinae Plane Block for Pain Relief in Liver Transplant Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the safety and effectiveness of the Erector Spinae Plane (ESP) block for providing pain relief during and after liver transplant surgeries. Participants will receive a bilateral ESP block with 0.2% ropivacaine on the day of their transplantation, followed by catheterization for continuous analgesia. The outcomes will be compared to a control group of liver transplant patients who do not receive any regional anesthesia techniques, focusing on the incidence of side effects and overall pain management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* impaired liver function - cirrhosis or chronic liver disease with the development of hypocoagulation (APTT \> 35 sec, INR \> 1.5), thrombocytopenia, patients requiring major abdominal surgery, age \> 18 years, written consent to participate in the study was obtained

Exclusion Criteria:

* Platelet count \<50x109, failed ESP catheterization unilateral or bilateral, failed epidural anesthesia attempt, history of allergy or hypersensitivity to local anesthetics, hepatopulmonary syndrome, patients on mechanical ventilation before surgery, patients on CRRT before surgery, refusal to participate in the study

Where it's running

• Universal Hospital Oberig
  Kyiv, Ukraine Recruiting

Study contacts

• Study coordinator: Nazarii Mysynchuk
• Email: n.mysynchuk@oberig.ua
• Phone: +380731624586

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.