Using Empagliflozin for Heart Failure Patients on Dialysis

Safety and Efficacy of Empagliflozin on Heart Failure Dialysis Patients

Not applicable Interventional Shahid Beheshti University of Medical Sciences · NCT05967156

This study is testing if the medication Empagliflozin can help heart failure patients on dialysis feel better and improve their heart and kidney function.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment15 (estimated)
SexAll
SponsorShahid Beheshti University of Medical Sciences Academic / other
Locations1 site (Tehran)
Trial IDNCT05967156 on ClinicalTrials.gov

What this trial studies

This study evaluates the safety and efficacy of Empagliflozin in patients with heart failure who are undergoing hemodialysis and still have some residual renal function. Participants will be monitored for changes in echocardiographic parameters, levels of pro-brain natriuretic peptide, diuresis volume, and serum acidity while on the medication. The goal is to determine if Empagliflozin can provide cardiac and renal benefits in this specific patient population.

Who should consider this trial

Good fit: Ideal candidates are heart failure patients on dialysis who still have some residual renal function.

Not a fit: Patients on dialysis with no residual urine will not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could improve heart and kidney function in dialysis patients with heart failure.

How similar studies have performed: While Empagliflozin has shown benefits in other populations, its use in dialysis patients is novel and not yet tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Heart failure on dialysis with residual renal function

Exclusion Criteria:

* Dialysis patients with no residual urine

Where this trial is running

Tehran

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heart FailureHemodialysis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.