Using electronic nudges to improve heart failure treatment in Amsterdam

PRagmatic Study Of Messaging to Providers of Patients With Heart Failure in Amsterdam UMC

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT06344910

This study is testing whether an electronic reminder system can help doctors in Amsterdam prescribe better treatments for patients with heart failure and reduced ejection fraction.

Quick facts

Study typeObservational
Enrollment900 (estimated)
Ages18 Years and up
SexAll
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (other)
Locations2 sites (Amsterdam and 1 other locations)
Trial IDNCT06344910 on ClinicalTrials.gov

What this trial studies

This observational study aims to evaluate the impact of an electronic nudge system that alerts clinicians to prescribe four key pharmacological classes for patients with heart failure and reduced ejection fraction (HFrEF) at outpatient clinics in Amsterdam. By utilizing electronic health records, the study seeks to enhance guideline-directed medical therapy for HFrEF patients. The study will involve a prospective cohort of patients receiving treatment for HFrEF, with data collected to assess the effectiveness of the intervention.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old receiving treatment for HFrEF with a documented reduced ejection fraction of less than 40%.

Not a fit: Patients who have opted out of using routine clinical data for research purposes will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved treatment adherence and outcomes for patients with heart failure.

How similar studies have performed: Other studies have shown promise in using electronic nudges to improve clinical decision-making, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 18 years
* Treatment for HFrEF at the outpatient clinic cardiology.
* Documented reduced ejection fraction of \<40% based on cardiac ultrasound or cardiac magnetic resonance imaging.

Exclusion Criteria:

* Opt-out for the use of routine clinical data for research purposes

Where this trial is running

Amsterdam and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Heart Failure With Reduced Ejection Fraction, electronic health records, electronic nudge, guideline directed medical therapy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.