Using Electrolysed Saline Rinse to Help Treat Chronic Periodontitis
Influence of Adjunctive Electrolysed Saline Rinse in Stage III Periodontitis Patients
This study is testing if a special saline rinse can help people with chronic gum disease get better results when used along with regular dental cleaning methods.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | University of Ljubljana Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Ljubljana) |
| Trial ID | NCT06692582 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of Electrolysed Oxidising Saline (EOS) as an adjunct treatment for chronic periodontitis, alongside standard non-surgical methods like root planing and scaling. Conducted at the Dental Clinic of University Medical Centre Ljubljana, it will involve 60 participants who will be randomly assigned to use either EOS, chlorhexidine mouthwash, or a placebo for one month. Clinical assessments will be performed to evaluate various periodontal parameters before and after the treatment period. The study aims to determine if EOS can improve periodontal health compared to traditional treatments.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 25-70 with moderate to advanced chronic periodontitis and specific clinical attachment loss criteria.
Not a fit: Patients with chronic systemic diseases, recent antibiotic treatment, or those undergoing chemotherapy will not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could provide a new, effective adjunct therapy for patients suffering from chronic periodontitis.
How similar studies have performed: While similar adjunct treatments have been explored, the specific use of Electrolysed Oxidising Saline in this context is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Clinical attachment loss ≥ 5 mm on at least two teeth in two different jaw quadrants; presence of stable occlusion and at least 16 teeth, among which at least 12 teeth are suitable for evaluation (excluding wisdom teeth, teeth with orthodontic wires, bridges, crowns, and implants). Exclusion Criteria: We will exclude individuals who: suffer from chronic systemic diseases (diabetes, cancer, HIV infection, metabolic bone diseases, and diseases that interfere with wound healing processes); are undergoing radiation or chemotherapy; are taking immunosuppressants, antiepileptic drugs, calcium antagonists, nonsteroidal anti-inflammatory drugs; have been treated with antibiotics in the past 12 months; have a known allergy to CHX; have undergone scaling and root planing or surgical periodontal treatment in the past year; are pregnant or breastfeeding.
Where this trial is running
Ljubljana
- University Medical Centre Ljubljana — Ljubljana, Slovenia (Recruiting)
Study contacts
- Study coordinator: Rok Gašperšič, PhD
- Email: rok.gaspersic@mf.uni-lj.si
- Phone: 0038615224889
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.