Using Electrolysed Saline Rinse to Help Treat Chronic Periodontitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of Electrolysed Oxidising Saline (EOS) as an adjunct treatment for chronic periodontitis, alongside standard non-surgical methods like root planing and scaling. Conducted at the Dental Clinic of University Medical Centre Ljubljana, it will involve 60 participants who will be randomly assigned to use either EOS, chlorhexidine mouthwash, or a placebo for one month. Clinical assessments will be performed to evaluate various periodontal parameters before and after the treatment period. The study aims to determine if EOS can improve periodontal health compared to traditional treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Clinical attachment loss ≥ 5 mm on at least two teeth in two different jaw quadrants; presence of stable occlusion and at least 16 teeth, among which at least 12 teeth are suitable for evaluation (excluding wisdom teeth, teeth with orthodontic wires, bridges, crowns, and implants).

Exclusion Criteria:

We will exclude individuals who: suffer from chronic systemic diseases (diabetes, cancer, HIV infection, metabolic bone diseases, and diseases that interfere with wound healing processes); are undergoing radiation or chemotherapy; are taking immunosuppressants, antiepileptic drugs, calcium antagonists, nonsteroidal anti-inflammatory drugs; have been treated with antibiotics in the past 12 months; have a known allergy to CHX; have undergone scaling and root planing or surgical periodontal treatment in the past year; are pregnant or breastfeeding.

Where it's running

• University Medical Centre Ljubljana
  Ljubljana, Slovenia Recruiting

Study contacts

• Study coordinator: Rok Gašperšič, PhD
• Email: rok.gaspersic@mf.uni-lj.si
• Phone: 0038615224889

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.