Clinical trial No longer in our active list Interventional Ages 16 and up

Using electroacupuncture to manage symptoms in cancer patients and survivors

Official title: Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors (EAST): A Feasibility Study

Run by University of California, Irvine · NCT05283577 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing whether electroacupuncture can help cancer patients and survivors feel better by reducing symptoms like fatigue, sleep problems, and mental distress.

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Quick facts

Study typeInterventional
Ages16 Years and up
SexAll
Enrollment88 (estimated)
SponsorUniversity of California, Irvine
Academic / other
Locations1 site (Irvine, California)
Trial IDNCT05283577 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include cancer patients aged 16 and older who have completed anti-cancer treatment and experience symptoms like fatigue, insomnia, or cognitive impairment.

Probably not a fit

Patients with severe psychiatric disorders, metastasis, or those currently receiving acupuncture therapy may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot trial evaluates the feasibility and efficacy of electroacupuncture (EA) as an intervention for symptom clusters in cancer patients and survivors. Participants will be randomly assigned to receive either EA or sham-EA over a 10-week treatment period, with weekly visits to assess changes in symptoms such as cognitive impairment, fatigue, psychological distress, and insomnia. The study also aims to analyze the impact of EA on specific biomarkers associated with these symptoms. The research will help determine the safety and effectiveness of EA in improving quality of life for cancer patients.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the quality of life for cancer patients and survivors by alleviating debilitating symptoms.

How similar studies have gone: While the use of electroacupuncture in cancer symptom management is emerging, this specific approach is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with cancer that have received anti-cancer treatment
* 16 years of age or older
* Life expectancy ≥ 6 months
* Complaints of one or more of the following symptoms: memory impairment/attention deficit, fatigue, insomnia, depression, or anxiety over the past 7 days

Exclusion Criteria:

* Presence of metastasis
* Severe needle phobia
* Severe psychiatric or medical disorders which would affect cognitive assessments
* Known bleeding disorder (e.g. hemophilia, Von Willebrand's disease, thrombocytopenia)
* Has pacemaker or other electronic metal implants
* Epilepsy
* Already receiving acupuncture therapy or received acupuncture treatment in the past 3 months.
* Breastfeeding, pregnant or are planning get pregnant during the study period

Additional exclusion criteria for optional neuroimaging procedure:

- Has any contraindications to fMRI including metal fragments/implants in the body, sever claustrophobia, and non-removable metal orthodontic braces, metallic retainers and oral wires.

Where it's running

  • UCI Health Susan Samueli Integrative Health Institute
    Irvine, California, United States
    Recruiting

Study contacts

  • Principal investigator: Alexandre Chan, PharmD — UCI
  • Study coordinator: Alexandre Chan, PharmD
  • Email: a.chan@uci.edu
  • Phone: 1-949-824-8896

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.