Using electroacupuncture to manage symptoms in cancer patients and survivors

Electroacupuncture for the Management of Symptom Clusters in Cancer Patients and Survivors (EAST): A Feasibility Study

NA · University of California, Irvine · NCT05283577

This study is testing whether electroacupuncture can help cancer patients and survivors feel better by reducing symptoms like fatigue, sleep problems, and mental distress.

Quick facts

PhaseNA
Study typeInterventional
Enrollment88 (estimated)
Ages16 Years and up
SexAll
SponsorUniversity of California, Irvine (other)
Locations1 site (Irvine, California)
Trial IDNCT05283577 on ClinicalTrials.gov

What this trial studies

This pilot trial evaluates the feasibility and efficacy of electroacupuncture (EA) as an intervention for symptom clusters in cancer patients and survivors. Participants will be randomly assigned to receive either EA or sham-EA over a 10-week treatment period, with weekly visits to assess changes in symptoms such as cognitive impairment, fatigue, psychological distress, and insomnia. The study also aims to analyze the impact of EA on specific biomarkers associated with these symptoms. The research will help determine the safety and effectiveness of EA in improving quality of life for cancer patients.

Who should consider this trial

Good fit: Ideal candidates include cancer patients aged 16 and older who have completed anti-cancer treatment and experience symptoms like fatigue, insomnia, or cognitive impairment.

Not a fit: Patients with severe psychiatric disorders, metastasis, or those currently receiving acupuncture therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the quality of life for cancer patients and survivors by alleviating debilitating symptoms.

How similar studies have performed: While the use of electroacupuncture in cancer symptom management is emerging, this specific approach is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients diagnosed with cancer that have received anti-cancer treatment
* 16 years of age or older
* Life expectancy ≥ 6 months
* Complaints of one or more of the following symptoms: memory impairment/attention deficit, fatigue, insomnia, depression, or anxiety over the past 7 days

Exclusion Criteria:

* Presence of metastasis
* Severe needle phobia
* Severe psychiatric or medical disorders which would affect cognitive assessments
* Known bleeding disorder (e.g. hemophilia, Von Willebrand's disease, thrombocytopenia)
* Has pacemaker or other electronic metal implants
* Epilepsy
* Already receiving acupuncture therapy or received acupuncture treatment in the past 3 months.
* Breastfeeding, pregnant or are planning get pregnant during the study period

Additional exclusion criteria for optional neuroimaging procedure:

- Has any contraindications to fMRI including metal fragments/implants in the body, sever claustrophobia, and non-removable metal orthodontic braces, metallic retainers and oral wires.

Where this trial is running

Irvine, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.