Using electrical stimulation to treat mild to moderate ulcerative colitis

A Multicenter Randomized Controlled Trial of Transcutaneous Electrical Acustimulation in the Treatment of Mild to Moderate Ulcerative Colitis

NA · Xijing Hospital · NCT06231264

This study is testing if a new electrical treatment can help people with mild to moderate ulcerative colitis feel better and improve their health.

Quick facts

PhaseNA
Study typeInterventional
Enrollment96 (estimated)
Ages18 Years and up
SexAll
SponsorXijing Hospital (other)
Locations4 sites (Xi'an, Shaanxi and 3 other locations)
Trial IDNCT06231264 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness and safety of transcutaneous electrical acustimulation in patients suffering from mild to moderate ulcerative colitis. Participants will receive either active treatment at designated sites or sham treatment to compare outcomes. The study aims to determine if this non-invasive approach can improve symptoms and overall health in affected individuals. Patients will be monitored for changes in their condition and any potential side effects.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with a diagnosis of mild to moderate ulcerative colitis who have not responded to at least one medical treatment.

Not a fit: Patients with treatment-naive ulcerative colitis or those with acute severe cases may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a new, non-invasive option for managing ulcerative colitis symptoms.

How similar studies have performed: While this approach is relatively novel, similar studies exploring electrical stimulation for gastrointestinal conditions have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ≥18 years
2. Ulcerative colitis diagnosed for at least 3 mouths.
3. Mayo score 4-10, Mayo endoscopic score 2-3 points
4. Resistant to at least one type of medical treatments

Exclusion Criteria:

1. Treatment-naive ulcerative colitis (no previous treatment)
2. Acute severe ulcerative colitis
3. Previous surgical treatment or severe colitis at imminent risk of surgery infective colitis
4. Other systemic diseases
5. Pregnancy and lactation
6. Allergic to the electrode patch

Where this trial is running

Xi'an, Shaanxi and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Ulcerative Colitis

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.