Using electrical stimulation to improve muscle function in patients undergoing hemodialysis
Efficacy of Combined Low- and High- Frequency Stimulation in Peripheral Muscle Function During Hemodialysis
NA · Hospital Sirio-Libanes · NCT03779126
This study is testing if using electrical stimulation can help improve muscle strength and overall well-being in people with chronic kidney disease who are on hemodialysis.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 56 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Hospital Sirio-Libanes (other) |
| Locations | 1 site (São Paulo) |
| Trial ID | NCT03779126 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of combined low- and high-frequency electrical stimulation on peripheral muscle function in patients with chronic kidney disease undergoing hemodialysis. Participants will be randomly assigned to one of four groups: low frequency, high frequency, combined low and high frequency, or sham stimulation. Each group will receive bilateral quadriceps stimulation for sixty minutes, three times a week, over a two-month period. The study aims to assess various health metrics, including muscle function, quality of life, and biochemical markers, before and after the intervention.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with chronic kidney disease who are currently on hemodialysis and have not engaged in regular physical activity for the past six months.
Not a fit: Patients with cognitive or motor deficits, those with pacemakers, or those who have abstained from hemodialysis sessions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance muscle function and overall quality of life for patients undergoing hemodialysis.
How similar studies have performed: Other studies have shown promising results with electrical stimulation in similar patient populations, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Chronic kidney disease * Classical hemodialysis * Over 18 years old * No pace maker * Without cognitive or motor deficit * No regular physical activity in the last six months Exclusion Criteria: * Abstention for more than two consecutive sessions or four in total * Inability to perform the tests
Where this trial is running
São Paulo
- Hospitalsiriolibanes — São Paulo, Brazil (RECRUITING)
Study contacts
- Principal investigator: Wellington PS Yamaguti, Phd — Hospital Sírio-Libanês
- Study coordinator: Wellington PS Yamaguti, Phd
- Email: wellington.psyamaguti@hsl.org.br
- Phone: 1133940200
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Chronic Kidney Diseases, Chronic Kidney Disease, Electrical stimulation