Using EEG to Distinguish Between Types of Stroke

Role of Electroencephalogram (EEG) in Differentiation Between Ischemic and Hemorrhagic Stroke and as a Predictor of Post-stroke Recovery

This study is testing if brain activity measured by EEG can help doctors tell the difference between two types of strokes and predict how well patients will recover.

Quick facts

• Study type: Observational
• Enrollment: 300 (estimated)
• Ages: 18 Years to 80 Years
• Sex: All
• Sponsor: Assiut University (other)
• Locations: 1 site (Asyut, Asyut Governorate)
• Trial ID: NCT06984965 on ClinicalTrials.gov

What this trial studies

This observational study investigates the electrical activity of the brain using EEG in patients with acute ischemic and hemorrhagic strokes. EEG recordings will be conducted within 72 hours of stroke onset to analyze differences in brain activity patterns associated with each stroke type. The study aims to determine if EEG can serve as a reliable tool for differentiating between these two conditions and predicting post-stroke recovery outcomes. Data will be collected at baseline and followed up over an average period of 3 to 6 months to assess recovery patterns.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 80 who have experienced their first-ever acute ischemic or hemorrhagic stroke within 72 hours.

Not a fit: Patients with transient ischemic attacks, those beyond 72 hours post-stroke, or those with certain neurological conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the accuracy of stroke diagnosis and improve recovery predictions for patients.

How similar studies have performed: While EEG has been used in stroke assessments, this specific approach to differentiate between ischemic and hemorrhagic strokes is relatively novel.

Eligibility criteria

Inclusion Criteria:

* Age above 18 and below 80 years.
* Acute Ischemic stroke: ischemic arteria cerebri media infarct confirmed by MRI.
* Acute Hemorrhagic stroke: spontaneous intraparenchymal bleeding confirmed by CT.
* Stroke onset \<72 hours before expected time of performing EEG.
* First-ever ischemic stroke.
* Measurable deficit on the National Institute of Health Stroke Scale (NIHSS).
* Able to give and sign informed consent.

Exclusion Criteria:

* Transient Ischemic Attacks (TIAs).
* Greater than 72 hours past the initial insult.
* Patients with subarachnoid haemorrhage, traumatic haemorrhage (epidural/subdural bleeding), cerebral venous sinus thrombosis, indication for urgent neurosurgical intervention.
* History of other central nervous system diseases.
* Any signs unfit for MRI/EEG scan.
* Injury or active infection of electrode cap placement area.
* Claustrophobia; recognition disorder.
* Known skull defect or head trauma.
* Previous neurological procedure (metallic implant, brain pace, cranial operation history).
* Significant physical impairment that would restrict the ability to use the portable EEG devices.
* Presence of malignancy or systemic rheumatic disease
* Non-stroke disease or lesion affecting the sensorimotor system.
* Alcohol or drug addiction.
* Presence of pump/shunt.
* Presence of Malignancy.
* Presence of severe cognitive impairment.
* History of epilepsy or taking medication due to epilepsy.

Where this trial is running

Asyut, Asyut Governorate

• Neurology Department, Faculty of Medicine, Assiut University — Asyut, Asyut Governorate, Egypt (RECRUITING)

Study contacts

• Study coordinator: Gena ELassall, Bachelor of medicine and gener

Conditions: Acute Ischemic Stroke, Acute Haemorrhagic Stroke, EEG, Acute Ischaemic Stroke, Stroke Recovery