Using DXA imaging to assess scoliosis in patients
A Pilot Study of the Use of Dual-Energy X-ray Absorptiometry (DXA) in Scoliosis
This study is testing a new type of imaging called iDXA to see if it can better measure spine curvature in people with scoliosis compared to regular x-rays.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 4 Years to 16 Years |
| Sex | All |
| Sponsor | Sheffield Children's NHS Foundation Trust Academic / other |
| Locations | 1 site (Sheffield) |
| Trial ID | NCT06512038 on ClinicalTrials.gov |
What this trial studies
This pilot study aims to evaluate the image quality of iDXA AP supine spinal images to accurately measure the curvature of the spine in patients with scoliosis. Participants will undergo routine standing or sitting spinal x-rays and will be approached to have an additional supine DXA image taken. The study will assess how patients perceive iDXA imaging compared to traditional x-rays and explore its potential benefits in brace design and monitoring. The study will involve a small cohort of 25 patients and will last for 9 months, with oversight from spinal surgeons and a radiologist.
Who should consider this trial
Good fit: Ideal candidates include adolescents aged 10-16 with Adolescent Idiopathic Scoliosis or children aged 4-9 with Juvenile Idiopathic Scoliosis, as well as patients with quadriplegic Cerebral Palsy who can lie still.
Not a fit: Patients who are unable to lie still for 1-2 minutes or whose parents cannot understand the study procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the accuracy of scoliosis assessments and enhance brace design for better patient outcomes.
How similar studies have performed: While this approach is relatively novel, previous studies have explored the use of imaging techniques in scoliosis assessment, but the specific application of iDXA imaging is less common.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with Adolescent Idiopathic Scoliosis (AIS, aged 10-16 years) or Juvenile Idiopathic Scoliosis (JIS, aged 4-9 years) having an x-ray to look for curve progression OR to guide design of a new brace. * Patients with quadriplegic Cerebral Palsy (CP) having an x-ray to look for curve progression. Within the age range for inclusion for patients with CP, the recruiting clinician will make a clinical judgement on whether the patient is able to lie still long enough to undertake the iDXA, before inviting the patient to take part. Exclusion Criteria: * Parents unable to understand the study procedures. * Patients unable to lie still for 1-2 minutes
Where this trial is running
Sheffield
- Sheffield Children's NHS Foundation Trust — Sheffield, United Kingdom (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.