Using discarded embryos to improve IVF techniques
Official title: Laboratory Evaluation of De-identified, Developmentally Arrested Embryos of Embryos Diagnosed as Having an Abnormal Number of Chromosomes for Optimization of Techniques for Assisted Reproduction
Run by Reproductive Medicine Associates of New Jersey · NCT01219335 · Data updated 2026-11-12
This study is testing ways to use leftover embryos from IVF to improve how embryos are handled in the lab, aiming to boost their quality and survival rates for people trying to conceive.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Reproductive Medicine Associates of New Jersey Academic / other |
| Locations | 1 site (Basking Ridge, New Jersey) |
| Status | Recruiting |
| Started | April 2003 |
| Main results expected | December 2028 |
| Study ends | December 2029 |
| Registry record updated | June 3, 2026 |
| Trial ID | NCT01219335 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study include individuals or couples undergoing IVF treatment who may benefit from advancements in embryo handling and assessment.
✕Probably not a fit
Patients who are not undergoing IVF or those with conditions unrelated to infertility may not receive any benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study focuses on utilizing discarded embryos to enhance laboratory practices and technology related to human embryo development and assisted reproductive technologies. The study aims to test various methods, including freezing techniques and micromanipulation, to improve embryo quality and survival rates. Additionally, it seeks to develop non-invasive tests for predicting embryo quality and optimize laboratory equipment and staff proficiency. By analyzing the early development of embryos, the study hopes to contribute valuable insights to the field of infertility treatment.
Why it matters
Potential benefit: If successful, this study could lead to improved IVF success rates and better outcomes for patients experiencing infertility.
How similar studies have gone: Other studies have shown success in improving IVF techniques through innovative approaches, making this study a continuation of ongoing advancements in the field.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: none Exclusion Criteria: none
Where it's running
-
Reproductive Medicine Associates of new Jersey
Basking Ridge, New Jersey, United States Recruiting
Study contacts
- Principal investigator: Thomas Molinaro, MD, MSCE — Reproductive Medicine Associates of New Jersey
- Study coordinator: Christine V Whitehead, BSN, RN
- Email: clinicalresearchteam@rmanj.com
- Phone: 973-656-2841
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
AI-assisted embryo selection on day 5 in IVF for infertility
This trial tests whether an AI-based embryo selection tool can help pick the best embryo for transfer on day 5 in IVF/ICSI to improve pregnancy chances for people with infertility.
-
Preserving sperm quality with aging through cryopreservation
This study tests whether freezing and thawing sperm can help keep younger-like DNA and molecular traits in men as they age.
-
Unstimulated Egg Retrieval with CAPA-IVM and Euploid Embryo Transfer
This study tests whether eggs can be collected without ovarian stimulation, matured in the lab, and used to create a single euploid embryo for transfer in infertility patients.
-
Ultra-Long GnRH-a Pretreatment Before Frozen Embryo Transfer for Deep Infiltrating Endometriosis
In people under 40 with deep infiltrating endometriosis and infertility, the study tests whether two injections of a GnRH agonist before hormone support improve pregnancy outcomes in their first frozen-thawed embryo transfer.
-
Endometrial Waves and Pregnancy in FET Cycles with Hormone Therapy
This study tests whether patterns of uterine contractions during hormone-prepared frozen embryo transfer affect pregnancy outcomes.
-
Environmental and lifestyle factors linked to ART success in infertility patients
This study follows 5,000 infertile men and women to see how environmental exposures and lifestyle relate to the success of assisted reproductive technology.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.