Using diode laser to enhance periodontal treatment

Impact of Diode Laser as an Adjunct to Professional Mechanical Plaque Removal (PMPR) in Patients With Periodontitis: A Randomized Clinical Trial

Not applicable Interventional University of Sulaimani · NCT06719674

This study is testing whether using a diode laser along with regular cleaning can help people with gum disease feel better and improve their oral health more than just cleaning alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorUniversity of Sulaimani Academic / other
Drugs / interventionsradiation
Locations1 site (Sulaymaniyah)
Trial IDNCT06719674 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of diode laser as an adjunct to professional mechanical plaque removal in patients with periodontitis. It aims to compare the effectiveness of this combined approach against conventional treatment alone by evaluating clinical parameters and salivary biomarkers. The study will assess improvements in periodontal health indicators such as probing pocket depth and clinical attachment loss. This is the first study to explore the impact of diode lasers on salivary biomarker levels in the context of periodontal therapy.

Who should consider this trial

Good fit: Ideal candidates are patients diagnosed with periodontitis who have at least three teeth with probing pocket depths of 5 mm or more.

Not a fit: Patients with diabetes, those on certain medications affecting healing, or who have received recent periodontal therapy may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved treatment outcomes for patients with periodontitis.

How similar studies have performed: While other studies have explored laser treatments in periodontal care, this specific approach focusing on salivary biomarkers is novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient with periodontitis.
* Patients having at least 3 teeth with PPD of 5 mm and above.

Exclusion Criteria:

* Patients with diabetes
* Patients on medication with an inhibitory or promoting effect on periodontal healing, including anticoagulants, anti-inflammatory drugs.
* Patients received antibiotics within the last three months.
* Pregnant or nursing women
* Patients receiving periodontal therapy within the last 3 months

Where this trial is running

Sulaymaniyah

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PeriodontitisPocket, PeriodontalNon surgical periodontal therapyDiode laserSalivary biomarkers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.